1W2F

Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016301	molecular_function	kinase activity
A	0032958	biological_process	inositol phosphate biosynthetic process
B	0016301	molecular_function	kinase activity
B	0032958	biological_process	inositol phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A1462

Chain	Residue
A	LYS264
A	LYS312
A	LYS419
A	HOH2026
A	HOH2125

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A1463

Chain	Residue
A	ARG285
A	MSE288
A	LYS312

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A1464

Chain	Residue
A	ARG319
A	HOH2144
A	HOH2145
A	TYR315

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B1462

Chain	Residue
B	LYS291
B	TYR315
B	ARG319

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15350214","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1W2D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15350214","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1W2C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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