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1W2A

Deacetoxycephalosporin C synthase (with his-tag) complexed with Fe(II) and ethylene glycol

Functional Information from GO Data
ChainGOidnamespacecontents
X0005506molecular_functioniron ion binding
X0009058biological_processbiosynthetic process
X0016491molecular_functionoxidoreductase activity
X0016706molecular_function2-oxoglutarate-dependent dioxygenase activity
X0017000biological_processantibiotic biosynthetic process
X0031418molecular_functionL-ascorbic acid binding
X0050599molecular_functiondeacetoxycephalosporin-C synthase activity
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE FE X1302
ChainResidue
XHIS183
XASP185
XHIS243
XEDO1301
XHOH2063
XHOH2082

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO X1300
ChainResidue
XARG160
XEDO1301
XHOH2079

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO X1301
ChainResidue
XHIS183
XASP185
XPHE264
XEDO1300
XFE1302
XHOH2063
XHOH2081
XHOH2082

Functional Information from PROSITE/UniProt
site_idPS00186
Number of Residues14
DetailsIPNS_2 Isopenicillin N synthase signature 2. LVfCGAiaTlvTgG
ChainResidueDetails
XLEU223-GLY236

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1qje
ChainResidueDetails
XMET180

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1qje
ChainResidueDetails
XTYR163

site_idCSA3
Number of Residues1
DetailsAnnotated By Reference To The Literature 1qje
ChainResidueDetails
XARG74

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1qje
ChainResidueDetails
XARG160

site_idMCSA1
Number of Residues1
DetailsM-CSA 137
ChainResidueDetails
XARG74steric hindrance

226707

PDB entries from 2024-10-30

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