1VUB

CCDB, A TOPOISOMERASE POISON FROM E. COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006276	biological_process	plasmid maintenance
A	0008657	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
A	0017053	cellular_component	transcription repressor complex
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0110001	cellular_component	toxin-antitoxin complex
A	2000104	biological_process	negative regulation of DNA-templated DNA replication
B	0005515	molecular_function	protein binding
B	0006276	biological_process	plasmid maintenance
B	0008657	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
B	0017053	cellular_component	transcription repressor complex
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0110001	cellular_component	toxin-antitoxin complex
B	2000104	biological_process	negative regulation of DNA-templated DNA replication
C	0005515	molecular_function	protein binding
C	0006276	biological_process	plasmid maintenance
C	0008657	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
C	0017053	cellular_component	transcription repressor complex
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0110001	cellular_component	toxin-antitoxin complex
C	2000104	biological_process	negative regulation of DNA-templated DNA replication
D	0005515	molecular_function	protein binding
D	0006276	biological_process	plasmid maintenance
D	0008657	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
D	0017053	cellular_component	transcription repressor complex
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0110001	cellular_component	toxin-antitoxin complex
D	2000104	biological_process	negative regulation of DNA-templated DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 102

Chain	Residue
A	HIS55
A	HIS85
A	ARG86

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 202

Chain	Residue
B	HIS55
B	ARG86

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 302

Chain	Residue
C	VAL54
C	HIS55
C	ARG86

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 402

Chain	Residue
D	ARG86
D	HIS55

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