1VS1
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 301 |
| Chain | Residue |
| A | CYS46 |
| A | HIS216 |
| A | GLU242 |
| A | ASP253 |
| A | PEP302 |
| A | HOH313 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 301 |
| Chain | Residue |
| B | ASP253 |
| B | PEP303 |
| B | HOH304 |
| B | CYS46 |
| B | HIS216 |
| B | GLU242 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 301 |
| Chain | Residue |
| C | CYS46 |
| C | HIS216 |
| C | GLU242 |
| C | ASP253 |
| C | PEP304 |
| C | HOH340 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 301 |
| Chain | Residue |
| D | CYS46 |
| D | HIS216 |
| D | GLU242 |
| D | ASP253 |
| D | PEP305 |
| D | HOH306 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP A 302 |
| Chain | Residue |
| A | ARG70 |
| A | LYS75 |
| A | GLN126 |
| A | GLY128 |
| A | ALA129 |
| A | ARG130 |
| A | LYS151 |
| A | ARG181 |
| A | HIS216 |
| A | GLU242 |
| A | MN301 |
| A | HOH313 |
| A | HOH318 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP B 303 |
| Chain | Residue |
| B | ARG70 |
| B | LYS75 |
| B | PRO76 |
| B | GLU108 |
| B | GLN126 |
| B | GLY128 |
| B | ALA129 |
| B | ARG130 |
| B | LYS151 |
| B | ARG181 |
| B | HIS216 |
| B | MN301 |
| B | HOH320 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP C 304 |
| Chain | Residue |
| C | ARG70 |
| C | LYS75 |
| C | PRO76 |
| C | GLU108 |
| C | GLN126 |
| C | GLY128 |
| C | ALA129 |
| C | ARG130 |
| C | LYS151 |
| C | ARG181 |
| C | HIS216 |
| C | MN301 |
| C | HOH340 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEP D 305 |
| Chain | Residue |
| D | ARG70 |
| D | LYS75 |
| D | GLN126 |
| D | GLY128 |
| D | ALA129 |
| D | ARG130 |
| D | LYS151 |
| D | ARG181 |
| D | HIS216 |
| D | GLU242 |
| D | MN301 |
| D | HOH326 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| A | HIS216 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| B | HIS216 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| C | HIS216 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| D | HIS216 |
