1VS0
Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003910 | molecular_function | DNA ligase (ATP) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| B | 0003910 | molecular_function | DNA ligase (ATP) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 9001 |
| Chain | Residue |
| B | APK481 |
| B | ASP483 |
| B | ASP522 |
| B | GLU613 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 9002 |
| Chain | Residue |
| A | APK481 |
| A | ASP483 |
| A | ASP522 |
| A | GLU613 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 9003 |
| Chain | Residue |
| B | HIS493 |
| B | GLU727 |
| B | CL9008 |
| B | ASP492 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 9004 |
| Chain | Residue |
| A | ASP492 |
| A | HIS493 |
| A | GLU727 |
| A | CL9007 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 9005 |
| Chain | Residue |
| A | ALA463 |
| A | APK481 |
| A | LYS635 |
| A | HOH9163 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 9006 |
| Chain | Residue |
| B | ALA463 |
| B | APK481 |
| B | HOH9118 |
| B | HOH9188 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 9007 |
| Chain | Residue |
| A | ASP492 |
| A | HIS493 |
| A | GLU727 |
| A | ARG748 |
| A | ZN9004 |
| A | HOH9220 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 9008 |
| Chain | Residue |
| B | ASP492 |
| B | HIS493 |
| B | HIS524 |
| B | GLU727 |
| B | ARG748 |
| B | ZN9003 |
| B | HOH9178 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 9009 |
| Chain | Residue |
| A | GLU454 |
| A | ASP456 |
| A | ASP750 |
| B | HIS699 |
| B | ASP701 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate; for ligase activity","evidences":[{"source":"PubMed","id":"12215643","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16476729","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17174332","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
