1VRY

Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor

Replaces:  1ZHD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:23994010, ECO:0000269|PubMed:25730860

Chain	Residue	Details
A	PRO-2-SER18

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site_id	SWS_FT_FI2
Number of Residues	10
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:23994010, ECO:0000269|PubMed:25730860

Chain	Residue	Details
A	ARG19-LYS29

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site_id	SWS_FT_FI3
Number of Residues	20
Details	TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:23994010, ECO:0000269|PubMed:25730860

Chain	Residue	Details
A	ALA30-ALA50

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site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Important for obstruction of the ion pore in the closed conformation => ECO:0000269|PubMed:25730860

Chain	Residue	Details
A	LEU9

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