1VP6

M.loti ion channel cylic nucleotide binding domain

Replaces:  1PF0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005221	molecular_function	intracellularly cyclic nucleotide-activated monoatomic cation channel activity
C	0005221	molecular_function	intracellularly cyclic nucleotide-activated monoatomic cation channel activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 356

Chain	Residue
A	GLY278

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 357

Chain	Residue
A	ARG252
A	ARG271
A	SER321
A	HIS323
A	HOH441

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 358

Chain	Residue
A	ARG307
A	HOH379

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 361

Chain	Residue
A	HOH385

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 362

Chain	Residue
A	PRO234
A	ARG264
A	HOH456

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 363

Chain	Residue
A	ARG349

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 364

Chain	Residue
A	ALA231
A	HOH432
A	HOH451
C	VAL224

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 365

Chain	Residue
A	GLY240
A	ALA242
A	VAL243

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 366

Chain	Residue
A	HOH439
C	HOH420

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 367

Chain	Residue
A	ARG249

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR C 356

Chain	Residue
C	ARG252
C	ARG271
C	SER321
C	HIS323

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR C 357

Chain	Residue
C	ARG252
C	ARG254
C	ARG271
C	SER321

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 358

Chain	Residue
C	ILE262
C	ARG307
C	HOH416

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR C 359

Chain	Residue
C	ARG349

---

site_id	BC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CMP A 368

Chain	Residue
A	VAL282
A	PHE296
A	GLY297
A	GLU298
A	MET299
A	ALA300
A	ARG307
A	SER308
A	ALA309
A	VAL311
A	ARG348
A	HOH375
A	HOH411
A	HOH431

---

site_id	BC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CMP C 360

Chain	Residue
C	VAL282
C	PHE296
C	GLY297
C	GLU298
C	MET299
C	ALA300
C	ARG307
C	SER308
C	ALA309
C	VAL311
C	ARG348
C	HOH363
C	HOH446
C	HOH468

---

Functional Information from PROSITE/UniProt

site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. ICrIGEpGDrMFFVveG

Chain	Residue	Details
A	ILE262-GLY278

---

site_id	PS00889
Number of Residues	18
Details	CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGEmALisgep......RSAtVsA

Chain	Residue	Details
A	PHE296-ALA313

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PDB","id":"1VP6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---