1VMK

Crystal structure of Purine nucleoside phosphorylase (TM1596) from Thermotoga maritima at 2.01 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006148	biological_process	inosine catabolic process
A	0006149	biological_process	deoxyinosine catabolic process
A	0006161	biological_process	deoxyguanosine catabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
A	0046115	biological_process	guanosine catabolic process
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0005829	cellular_component	cytosol
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006148	biological_process	inosine catabolic process
B	0006149	biological_process	deoxyinosine catabolic process
B	0006161	biological_process	deoxyguanosine catabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
B	0046115	biological_process	guanosine catabolic process
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0005829	cellular_component	cytosol
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006148	biological_process	inosine catabolic process
C	0006149	biological_process	deoxyinosine catabolic process
C	0006161	biological_process	deoxyguanosine catabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
C	0046115	biological_process	guanosine catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 266

Chain	Residue
B	HOH322
B	HOH358
B	HOH391
B	HOH397

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GUN A 300

Chain	Residue
A	GLU186
A	VAL202
A	GLY203
A	MET204
A	THR227
A	ASN228
A	HOH339
A	ALA111
A	ALA112
A	GLY113
A	VAL180
A	TYR185

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GUN B 300

Chain	Residue
B	ALA111
B	ALA112
B	GLY113
B	VAL180
B	GLU186
B	VAL202
B	GLY203
B	MET204
B	THR227
B	ASN228
B	HOH332

---

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GUN C 300

Chain	Residue
C	ALA111
C	ALA112
C	GLY113
C	VAL180
C	TYR185
C	GLU186
C	VAL202
C	GLY203
C	MET204
C	THR227
C	ASN228
C	HOH322
C	HOH345

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
A	HIS81
A	ASN228
A	GLU84

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
B	HIS81
B	ASN228
B	GLU84

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
C	HIS81
C	ASN228
C	GLU84

---