1VLP
Crystal structure of a putative nicotinate phosphoribosyltransferase (yor209c, npt1) from saccharomyces cerevisiae at 1.75 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000183 | biological_process | rDNA heterochromatin formation |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0019358 | biological_process | nicotinate nucleotide salvage |
| A | 0031509 | biological_process | subtelomeric heterochromatin formation |
| A | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| B | 0000183 | biological_process | rDNA heterochromatin formation |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0019358 | biological_process | nicotinate nucleotide salvage |
| B | 0031509 | biological_process | subtelomeric heterochromatin formation |
| B | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| C | 0000183 | biological_process | rDNA heterochromatin formation |
| C | 0000781 | cellular_component | chromosome, telomeric region |
| C | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0009435 | biological_process | NAD+ biosynthetic process |
| C | 0019358 | biological_process | nicotinate nucleotide salvage |
| C | 0031509 | biological_process | subtelomeric heterochromatin formation |
| C | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| D | 0000183 | biological_process | rDNA heterochromatin formation |
| D | 0000781 | cellular_component | chromosome, telomeric region |
| D | 0004516 | molecular_function | nicotinate phosphoribosyltransferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0009435 | biological_process | NAD+ biosynthetic process |
| D | 0019358 | biological_process | nicotinate nucleotide salvage |
| D | 0031509 | biological_process | subtelomeric heterochromatin formation |
| D | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 500 |
| Chain | Residue |
| A | SER327 |
| A | SER329 |
| A | GLY354 |
| A | THR355 |
| A | HOH569 |
| A | HOH574 |
| A | HOH599 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 500 |
| Chain | Residue |
| B | GLY354 |
| B | THR355 |
| B | HOH649 |
| B | HOH653 |
| B | SER327 |
| B | SER329 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 500 |
| Chain | Residue |
| C | SER327 |
| C | SER329 |
| C | GLY354 |
| C | THR355 |
| C | HOH515 |
| C | HOH526 |
| C | HOH613 |
| C | HOH784 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 500 |
| Chain | Residue |
| D | SER327 |
| D | SER329 |
| D | GLY354 |
| D | THR355 |
| D | HOH544 |
| D | HOH556 |
| D | HOH637 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 501 |
| Chain | Residue |
| C | TYR36 |
| C | ASN38 |
| C | LEU117 |
| C | HOH534 |
| C | HOH694 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 501 |
| Chain | Residue |
| A | TYR36 |
| A | ASN38 |
| A | LEU117 |
| A | HOH633 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 501 |
| Chain | Residue |
| B | TYR36 |
| B | ASN38 |
| B | LEU117 |
| B | HOH524 |
| B | HOH654 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| A | THR31 |
| A | VAL32 |
| A | THR33 |
| A | SER122 |
| A | GLU382 |
| A | ASN384 |
| A | GLY385 |
| B | LYS111 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 502 |
| Chain | Residue |
| C | THR275 |
| C | ASP276 |
| C | ASP393 |
| C | TYR414 |
| C | THR415 |
| C | HOH719 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 503 |
| Chain | Residue |
| A | LYS111 |
| B | THR31 |
| B | VAL32 |
| B | THR33 |
| B | SER122 |
| B | GLU382 |
| B | ASN384 |
| B | GLY385 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MES A 502 |
| Chain | Residue |
| A | ASP204 |
| B | LYS220 |
| B | LYS221 |
| B | GLY223 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9HJ28","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16154095","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphohistidine; by autocatalysis","evidences":[{"source":"UniProtKB","id":"P22253","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
