1VKO

Crystal structure of inositol-3-phosphate synthase (ce21227) from Caenorhabditis elegans at 2.30 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004512	molecular_function	inositol-3-phosphate synthase activity
A	0006021	biological_process	inositol biosynthetic process
A	0008654	biological_process	phospholipid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE K A 526

Chain	Residue
A	ASN76
A	ASN346
A	ASP400
A	ASP428
A	SER429
A	NAD601
A	HOH684

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 527

Chain	Residue
A	HIS115

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 528

Chain	Residue
A	TYR104

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 529

Chain	Residue
A	SER120

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 530

Chain	Residue
A	ASP382

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site_id	AC6
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAD A 601

Chain	Residue
A	VAL70
A	GLY71
A	GLY73
A	GLY74
A	ASN75
A	ASN76
A	ASP148
A	ILE149
A	SER184
A	ILE185
A	ARG198
A	THR236
A	ALA237
A	ASN238
A	THR239
A	GLY287
A	SER288
A	ASP312
A	PHE313
A	SER315
A	ASN347
A	ASP348
A	LYS361
A	ASP428
A	ALA432
A	LYS472
A	K526
A	POP602
A	HOH630
A	HOH682

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site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE POP A 602

Chain	Residue
A	SER315
A	GLY316
A	GLN317
A	THR318
A	LYS361
A	LYS365
A	LYS402
A	LYS472
A	NAD601
A	HOH691

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