Functional Information from GO Data
Chain | GOid | namespace | contents |
U | 0004252 | molecular_function | serine-type endopeptidase activity |
U | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 U 401 |
Chain | Residue |
U | LYS61 |
U | HIS100 |
U | THR177 |
U | LYS179 |
U | MET180 |
U | HOH429 |
U | HOH468 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 U 403 |
Chain | Residue |
U | GLY193 |
U | SER195 |
U | 5IN300 |
U | HIS57 |
U | GLN192 |
site_id | AC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE 5IN U 300 |
Chain | Residue |
U | LEU97 |
U | HIS99 |
U | ASP189 |
U | SER190 |
U | GLN192 |
U | SER195 |
U | VAL213 |
U | SER214 |
U | TRP215 |
U | GLY216 |
U | ARG217 |
U | GLY219 |
U | GLY226 |
U | SO4403 |
U | HOH430 |
U | HOH493 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
Chain | Residue | Details |
U | ILE53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
Chain | Residue | Details |
U | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
U | HIS57 | |
U | ASP102 | |
U | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Cleavage; during zymogen activation |
Chain | Residue | Details |
U | PHE14 | |
Chain | Residue | Details |
U | SER146 | |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
Chain | Residue | Details |
U | ASN145 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | ASP102 | |
U | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | SER195 | |
U | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | SER195 | |
U | GLY193 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | ASP102 | |
U | SER195 | |
U | GLY193 | |
U | HIS57 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | ASP102 | |
U | SER195 | |
U | HIS57 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
U | ASP102 | |
U | SER195 | |
U | HIS57 | |
U | GLY196 | |