1VH3

Crystal structure of CMP-KDO synthetase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
A	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
A	0044281	biological_process	small molecule metabolic process
A	1901137	biological_process	carbohydrate derivative biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0044281	biological_process	small molecule metabolic process
B	1901137	biological_process	carbohydrate derivative biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019294	biological_process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
C	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
C	0044281	biological_process	small molecule metabolic process
C	1901137	biological_process	carbohydrate derivative biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE CMK A 263

Chain	Residue
A	PRO8
A	ASP100
A	VAL142
A	ARG157
A	LYS175
A	HIS185
A	TYR189
A	GLU214
A	GLN215
A	HOH287
A	HOH294
A	ALA9
A	HOH297
A	HOH304
A	ARG10
A	HIS72
A	ASN73
A	SER74
A	ARG78
A	GLN98
A	GLY99

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site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE CMK B 263

Chain	Residue
A	ARG164
B	PRO8
B	ALA9
B	ARG10
B	LYS19
B	HIS72
B	ASN73
B	SER74
B	GLY75
B	ARG78
B	GLN98
B	GLY99
B	ASP100
B	ASN140
B	VAL142
B	ARG157
B	HIS185
B	TYR189
B	LYS212
B	LEU213
B	GLU214
B	GLN215
B	VAL238
B	HOH287

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1hv9

Chain	Residue	Details
B	ARG15

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1hv9

Chain	Residue	Details
C	ARG15

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