Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
C | 0004252 | molecular_function | serine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 C 357 |
Chain | Residue |
B | GLU21 |
C | ASP153 |
C | ARG154 |
C | GLN156 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 358 |
Chain | Residue |
B | SER92 |
C | TRP237 |
B | LYS36 |
site_id | AC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE V36 C 358 |
Chain | Residue |
B | HIS57 |
C | SER189 |
C | SER190 |
C | CYS191 |
C | MET192 |
C | GLY193 |
C | ASP194 |
C | SER195 |
C | VAL213 |
C | SER214 |
C | TRP215 |
C | GLY216 |
C | SER217 |
C | HOH332 |
C | HOH334 |
C | HOH338 |
site_id | CAT |
Number of Residues | 4 |
Details | THE CATALYTIC SITE WHICH INCLUDES THE MODIFIED SERINE THAT HAS THE BORONIC ACID INHIBITOR COVALENTLY ATTACHED. |
Chain | Residue |
B | HIS57 |
B | ASP102 |
C | SER195 |
C | V36358 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
Chain | Residue | Details |
B | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
Chain | Residue | Details |
C | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
C | SER195 | |
B | ASP102 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
C | SER195 | |
C | GLY193 | |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
C | SER195 | |
C | GLY196 | |
B | ASP102 | |
B | HIS57 | |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
C | GLY193 | electrostatic stabiliser |
C | SER195 | covalent catalysis |
C | GLY196 | electrostatic stabiliser |