1VFX

Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-AlFx

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003777	molecular_function	microtubule motor activity
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008017	molecular_function	microtubule binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	SER104
A	AF3400
A	ADP500

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AF3 A 400

Chain	Residue
A	THR99
A	SER215
A	ASP248
A	ADP500
A	MG501

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE TRS A 401

Chain	Residue
A	ARG18

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE TRS A 402

Chain	Residue
A	SER33

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site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A 500

Chain	Residue
A	ARG11
A	ARG13
A	PRO14
A	ASP64
A	ILE65
A	TYR67
A	GLN98
A	THR99
A	GLY100
A	ALA101
A	GLY102
A	LYS103
A	SER104
A	TYR105
A	AF3400
A	MG501
A	HOH511

---

Functional Information from PROSITE/UniProt

site_id	PS00411
Number of Residues	12
Details	KINESIN_MOTOR_1 Kinesin motor domain signature. SKIsLVDLAGSE

Chain	Residue	Details
A	SER242-GLU253

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P56536","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18806800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35132656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15286375","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EO9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EOB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1goj

Chain	Residue	Details
A	GLY251

---