1VF5

Crystal Structure of Cytochrome b6f Complex from M.laminosus

Replaces:  1UM3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
A	0009055	molecular_function	electron transfer activity
A	0009579	cellular_component	thylakoid
A	0015979	biological_process	photosynthesis
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0022904	biological_process	respiratory electron transport chain
A	0031676	cellular_component	plasma membrane-derived thylakoid membrane
A	0042651	cellular_component	thylakoid membrane
A	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
A	0046872	molecular_function	metal ion binding
B	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
B	0009055	molecular_function	electron transfer activity
B	0009579	cellular_component	thylakoid
B	0009767	biological_process	photosynthetic electron transport chain
B	0015979	biological_process	photosynthesis
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0031676	cellular_component	plasma membrane-derived thylakoid membrane
B	0042651	cellular_component	thylakoid membrane
B	0043229	cellular_component	intracellular organelle
B	0045156	molecular_function	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
C	0005506	molecular_function	iron ion binding
C	0009055	molecular_function	electron transfer activity
C	0009579	cellular_component	thylakoid
C	0015979	biological_process	photosynthesis
C	0016020	cellular_component	membrane
C	0020037	molecular_function	heme binding
C	0031676	cellular_component	plasma membrane-derived thylakoid membrane
C	0042651	cellular_component	thylakoid membrane
C	0043229	cellular_component	intracellular organelle
C	0046872	molecular_function	metal ion binding
D	0005886	cellular_component	plasma membrane
D	0009496	molecular_function	plastoquinol--plastocyanin reductase activity
D	0009579	cellular_component	thylakoid
D	0015979	biological_process	photosynthesis
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0031676	cellular_component	plasma membrane-derived thylakoid membrane
D	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0055085	biological_process	transmembrane transport
E	0009055	molecular_function	electron transfer activity
E	0009512	cellular_component	cytochrome b6f complex
E	0009579	cellular_component	thylakoid
E	0015979	biological_process	photosynthesis
E	0016020	cellular_component	membrane
E	0031676	cellular_component	plasma membrane-derived thylakoid membrane
E	0042651	cellular_component	thylakoid membrane
E	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
F	0009055	molecular_function	electron transfer activity
F	0009512	cellular_component	cytochrome b6f complex
F	0009579	cellular_component	thylakoid
F	0015979	biological_process	photosynthesis
F	0016020	cellular_component	membrane
F	0031676	cellular_component	plasma membrane-derived thylakoid membrane
F	0042651	cellular_component	thylakoid membrane
G	0009512	cellular_component	cytochrome b6f complex
G	0009579	cellular_component	thylakoid
G	0015979	biological_process	photosynthesis
G	0016020	cellular_component	membrane
G	0017004	biological_process	cytochrome complex assembly
G	0031676	cellular_component	plasma membrane-derived thylakoid membrane
G	0042651	cellular_component	thylakoid membrane
G	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
H	0009055	molecular_function	electron transfer activity
H	0009512	cellular_component	cytochrome b6f complex
H	0009579	cellular_component	thylakoid
H	0015979	biological_process	photosynthesis
H	0016020	cellular_component	membrane
H	0017004	biological_process	cytochrome complex assembly
H	0031676	cellular_component	plasma membrane-derived thylakoid membrane
H	0042651	cellular_component	thylakoid membrane
H	0043229	cellular_component	intracellular organelle
H	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
N	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
N	0009055	molecular_function	electron transfer activity
N	0009579	cellular_component	thylakoid
N	0015979	biological_process	photosynthesis
N	0016020	cellular_component	membrane
N	0016491	molecular_function	oxidoreductase activity
N	0022904	biological_process	respiratory electron transport chain
N	0031676	cellular_component	plasma membrane-derived thylakoid membrane
N	0042651	cellular_component	thylakoid membrane
N	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
N	0046872	molecular_function	metal ion binding
O	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
O	0009055	molecular_function	electron transfer activity
O	0009579	cellular_component	thylakoid
O	0009767	biological_process	photosynthetic electron transport chain
O	0015979	biological_process	photosynthesis
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0031676	cellular_component	plasma membrane-derived thylakoid membrane
O	0042651	cellular_component	thylakoid membrane
O	0043229	cellular_component	intracellular organelle
O	0045156	molecular_function	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
O	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
P	0005506	molecular_function	iron ion binding
P	0009055	molecular_function	electron transfer activity
P	0009579	cellular_component	thylakoid
P	0015979	biological_process	photosynthesis
P	0016020	cellular_component	membrane
P	0020037	molecular_function	heme binding
P	0031676	cellular_component	plasma membrane-derived thylakoid membrane
P	0042651	cellular_component	thylakoid membrane
P	0043229	cellular_component	intracellular organelle
P	0046872	molecular_function	metal ion binding
Q	0005886	cellular_component	plasma membrane
Q	0009496	molecular_function	plastoquinol--plastocyanin reductase activity
Q	0009579	cellular_component	thylakoid
Q	0015979	biological_process	photosynthesis
Q	0016020	cellular_component	membrane
Q	0016491	molecular_function	oxidoreductase activity
Q	0031676	cellular_component	plasma membrane-derived thylakoid membrane
Q	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
Q	0046872	molecular_function	metal ion binding
Q	0051536	molecular_function	iron-sulfur cluster binding
Q	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Q	0055085	biological_process	transmembrane transport
R	0009055	molecular_function	electron transfer activity
R	0009512	cellular_component	cytochrome b6f complex
R	0009579	cellular_component	thylakoid
R	0015979	biological_process	photosynthesis
R	0016020	cellular_component	membrane
R	0031676	cellular_component	plasma membrane-derived thylakoid membrane
R	0042651	cellular_component	thylakoid membrane
R	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
S	0009055	molecular_function	electron transfer activity
S	0009512	cellular_component	cytochrome b6f complex
S	0009579	cellular_component	thylakoid
S	0015979	biological_process	photosynthesis
S	0016020	cellular_component	membrane
S	0031676	cellular_component	plasma membrane-derived thylakoid membrane
S	0042651	cellular_component	thylakoid membrane
T	0009512	cellular_component	cytochrome b6f complex
T	0009579	cellular_component	thylakoid
T	0015979	biological_process	photosynthesis
T	0016020	cellular_component	membrane
T	0017004	biological_process	cytochrome complex assembly
T	0031676	cellular_component	plasma membrane-derived thylakoid membrane
T	0042651	cellular_component	thylakoid membrane
T	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
U	0009055	molecular_function	electron transfer activity
U	0009512	cellular_component	cytochrome b6f complex
U	0009579	cellular_component	thylakoid
U	0015979	biological_process	photosynthesis
U	0016020	cellular_component	membrane
U	0017004	biological_process	cytochrome complex assembly
U	0031676	cellular_component	plasma membrane-derived thylakoid membrane
U	0042651	cellular_component	thylakoid membrane
U	0043229	cellular_component	intracellular organelle
U	0045158	molecular_function	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A 301

Chain	Residue
A	PHE44
A	ARG83
A	HIS86
A	ALA90
A	MET93
A	PHE131
A	GLY135
A	LEU138
A	PRO139
A	HIS187
A	THR188
A	GLN47
N	PHE189
A	PHE48
A	GLY51
A	PHE52
A	MET54
A	THR55
A	TYR58
A	VAL69

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM A 302

Chain	Residue
A	TYR34
A	GLY37
A	GLY38
A	LEU41
A	HIS100
A	ARG103
A	VAL104
A	GLY109
A	ARG114
A	TRP118
A	GLY121
A	VAL122
A	ALA125
A	THR128
A	MET199
A	HIS202
A	LYS208
A	GLN209
A	HEM303

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM A 303

Chain	Residue
A	ASN31
A	TYR34
A	CYS35
A	GLY38
A	LEU41
A	PHE203
A	ILE206
A	LYS208
A	HEM302
A	PL9305
A	HOH306
B	PHE40

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE TDS A 304

Chain	Residue
A	SER130
A	THR134
A	TYR183
A	ALA186
A	VAL190
B	PHE85
B	LEU88
B	CLA201
N	OPC1306

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PL9 A 305

Chain	Residue
A	TYR25
A	HEM303
B	OPC307
D	THR28
D	OPC306

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OPC D 306

Chain	Residue
A	PHE48
A	PL9305
B	OPC307
D	LEU35
D	LEU38
D	VAL39
D	PHE42

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OPC B 307

Chain	Residue
A	LYS24
A	PL9305
B	ASN34
B	TYR38
D	GLN17
D	OPC306

---

site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CLA B 201

Chain	Residue
A	VAL101
A	TYR105
A	ALA125
A	TDS304
B	TYR80
B	PRO83
B	VAL84
B	MET101
B	ALA102
B	VAL104
B	ILE132
B	PHE133
B	GLY136
B	THR140

---

site_id	AC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM C 301

Chain	Residue
C	ASN71
C	VAL72
C	GLY73
C	ALA74
C	GLY156
C	ARG157
C	GLY158
C	ILE160
C	TYR161
C	TYR1
C	PRO2
C	ALA5
C	CYS22
C	CYS25
C	HIS26
C	GLN60

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FES D 200

Chain	Residue
D	CYS108
D	HIS110
D	LEU111
D	GLY112
D	CYS113
D	CYS126
D	HIS129
D	SER131

---

site_id	BC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE BCR E 101

Chain	Residue
A	PHE33
A	ILE39
B	GLY46
E	ALA13
E	PHE16
E	GLY17
E	VAL20
F	ILE16
F	PHE17
F	TRP20
G	PHE22
G	ALA25

---

site_id	BC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM N 301

Chain	Residue
A	PHE189
N	PHE44
N	GLN47
N	GLY51
N	PHE52
N	MET54
N	THR55
N	VAL69
N	ARG83
N	HIS86
N	ARG87
N	MET93
N	PHE131
N	GLY132
N	GLY135
N	PRO139
N	HIS187
N	THR188

---

site_id	BC4
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM N 302

Chain	Residue
N	TYR34
N	GLY37
N	GLY38
N	MET97
N	HIS100
N	ARG103
N	VAL104
N	GLY109
N	PHE110
N	ARG114
N	TRP118
N	GLY121
N	VAL122
N	ALA125
N	THR128
N	MET199
N	HIS202
N	PHE203
N	GLY210
N	HEM303
N	HOH1307

---

site_id	BC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM N 303

Chain	Residue
N	TYR34
N	CYS35
N	GLY38
N	LEU41
N	THR42
N	PHE203
N	ILE206
N	HEM302
N	HOH1307
O	VAL39
O	PHE40
O	VAL43
O	ILE44
Q	PL91305
T	ARG31

---

site_id	BC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TDS N 1304

Chain	Residue
N	SER130
N	THR134
N	VAL151
N	VAL154
N	LEU169
N	ARG182
N	TYR183
N	ALA186
N	VAL190
N	LEU191
O	PRO77
O	LEU81
O	LEU88
O	CLA1201

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PL9 Q 1305

Chain	Residue
N	HEM303
O	TYR38
Q	PHE24
Q	THR28
Q	LEU38
Q	OPC1307

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE OPC N 1306

Chain	Residue
A	LEU168
A	TDS304
N	LEU200
Q	PHE42

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OPC Q 1307

Chain	Residue
O	ASP35
O	TYR38
P	LYS276
Q	GLN17
Q	PHE24
Q	PL91305

---

site_id	CC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CLA O 1201

Chain	Residue
N	ILE98
N	VAL101
N	PHE102
N	TDS1304
O	TYR80
O	PRO83
O	VAL84
O	ILE87
O	VAL104
O	PRO105
O	LEU106
O	ILE132
O	PHE133
O	GLY136
O	THR140

---

site_id	CC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM P 301

Chain	Residue
P	TYR1
P	PRO2
P	ALA5
P	CYS22
P	CYS25
P	HIS26
P	GLN60
P	ASN71
P	VAL72
P	GLY73
P	ALA74
P	GLY156
P	ARG157
P	GLY158
P	ILE160
P	TYR161

---

site_id	CC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FES Q 1200

Chain	Residue
Q	CYS108
Q	HIS110
Q	LEU111
Q	GLY112
Q	CYS113
Q	CYS126
Q	CYS128
Q	HIS129
Q	SER131

---

site_id	CC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE BCR R 1101

Chain	Residue
N	PHE33
N	ILE39
N	MET96
N	LEU99
R	ALA13
R	PHE16
R	GLY17
R	VAL20
S	ILE16
S	PHE17
S	TRP20
T	PHE22
T	ALA25
T	GLN28

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_00395, ECO:0000305|PubMed:14526088

Chain	Residue	Details
H	ILE3-VAL23
U	ILE3-VAL23
P	VAL45
P	LEU70
N	LYS111-GLU115
N	ARG207-LEU215

---

site_id	SWS_FT_FI2
Number of Residues	44
Details	TRANSMEM: Helical => ECO:0000305|PubMed:14526088

Chain	Residue	Details
D	LEU21-ILE43
Q	LEU21-ILE43
P	SER66
P	GLY69
O	LEU95-GLU115
O	THR131-LEU151
N	LEU116-TYR136
N	ALA186-ILE206

---

site_id	SWS_FT_FI3
Number of Residues	270
Details	TOPO_DOM: Lumenal, thylakoid => ECO:0000305|PubMed:14526088

Chain	Residue	Details
D	PRO44-VAL179
Q	PRO44-VAL179
O	LEU57-LYS94
O	ASP152-PHE160

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:14526088

Chain	Residue	Details
D	CYS108
D	HIS110
D	CYS126
D	HIS129
Q	CYS108
Q	HIS110
Q	CYS126
Q	HIS129

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:14526088, ECO:0000269|PubMed:16371475, ECO:0007744|PDB:1VF5, ECO:0007744|PDB:2D2C

Chain	Residue	Details
A	ARG83
N	ARG83

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	BINDING: axial binding residue => ECO:0000269|PubMed:14526088, ECO:0000269|PubMed:16371475, ECO:0007744|PDB:1VF5, ECO:0007744|PDB:2D2C

Chain	Residue	Details
A	HIS86
A	HIS100
A	HIS187
A	HIS202
N	HIS86
N	HIS100
N	HIS187
N	HIS202

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14526088, ECO:0007744|PDB:1VF5

Chain	Residue	Details
A	ARG103
A	LYS208
N	ARG103
N	LYS208

---