1VF3
cGSTA1-1 in complex with glutathione conjugate of CDNB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0006805 | biological_process | xenobiotic metabolic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GDN A 2500 |
| Chain | Residue |
| A | TYR9 |
| A | PHE111 |
| A | MET222 |
| A | TYR223 |
| A | VAL226 |
| A | HOH4045 |
| A | HOH4075 |
| A | HOH4089 |
| A | HOH4136 |
| B | ASP1101 |
| B | ARG1131 |
| A | GLY14 |
| A | LYS15 |
| A | GLN54 |
| A | VAL55 |
| A | GLN67 |
| A | THR68 |
| A | LEU107 |
| A | SER108 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GDN B 3600 |
| Chain | Residue |
| A | ASP101 |
| A | ARG131 |
| B | TYR1009 |
| B | LYS1015 |
| B | GLN1054 |
| B | VAL1055 |
| B | GLN1067 |
| B | THR1068 |
| B | LEU1107 |
| B | SER1108 |
| B | PHE1111 |
| B | MET1222 |
| B | TYR1223 |
| B | HOH4042 |
| B | HOH4148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 244 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1VF1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VF3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | TYR9 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | TYR1009 |
