Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1VEW

MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004784	molecular_function	superoxide dismutase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006801	biological_process	superoxide metabolic process
A	0006979	biological_process	response to oxidative stress
A	0009408	biological_process	response to heat
A	0010447	biological_process	response to acidic pH
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019430	biological_process	removal of superoxide radicals
A	0030145	molecular_function	manganese ion binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0071291	biological_process	cellular response to selenium ion
B	0003677	molecular_function	DNA binding
B	0004784	molecular_function	superoxide dismutase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006801	biological_process	superoxide metabolic process
B	0006979	biological_process	response to oxidative stress
B	0009408	biological_process	response to heat
B	0010447	biological_process	response to acidic pH
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0019430	biological_process	removal of superoxide radicals
B	0030145	molecular_function	manganese ion binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0071291	biological_process	cellular response to selenium ion
C	0003677	molecular_function	DNA binding
C	0004784	molecular_function	superoxide dismutase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006801	biological_process	superoxide metabolic process
C	0006979	biological_process	response to oxidative stress
C	0009408	biological_process	response to heat
C	0010447	biological_process	response to acidic pH
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0019430	biological_process	removal of superoxide radicals
C	0030145	molecular_function	manganese ion binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0071291	biological_process	cellular response to selenium ion
D	0003677	molecular_function	DNA binding
D	0004784	molecular_function	superoxide dismutase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006801	biological_process	superoxide metabolic process
D	0006979	biological_process	response to oxidative stress
D	0009408	biological_process	response to heat
D	0010447	biological_process	response to acidic pH
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0030145	molecular_function	manganese ion binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding
D	0071291	biological_process	cellular response to selenium ion

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 206

Chain	Residue
A	HIS26
A	HIS81
A	ASP167
A	HIS171
A	OH207

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OH A 207

Chain	Residue
A	HIS81
A	GLN146
A	ASP167
A	TRP169
A	HIS171
A	MN206

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 206

Chain	Residue
B	HIS26
B	HIS81
B	ASP167
B	HIS171
B	OH207

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OH B 207

Chain	Residue
B	HIS81
B	GLN146
B	ASP167
B	TRP169
B	HIS171
B	MN206

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 206

Chain	Residue
C	HIS26
C	HIS81
C	ASP167
C	HIS171
C	OH207

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OH C 207

Chain	Residue
C	HIS81
C	GLN146
C	ASP167
C	TRP169
C	HIS171
C	MN206

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 206

Chain	Residue
D	HIS26
D	HIS81
D	ASP167
D	HIS171
D	OH207

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OH D 207

Chain	Residue
D	HIS81
D	GLN146
D	ASP167
D	TRP169
D	HIS171
D	MN206

site_id	MN1
Number of Residues	6
Details	MANGANESE-BOUND ACTIVE SITE ON CHAIN A. CATALYTIC REDOX CENTER.

Chain	Residue
A	MN206
A	HIS26
A	HIS81
A	ASP167
A	HIS171
A	OH207

site_id	MN2
Number of Residues	6
Details	MANGANESE-BOUND ACTIVE SITE ON CHAIN B. CATALYTIC REDOX CENTER.

Chain	Residue
B	ASP167
B	HIS171
B	OH207
B	MN206
B	HIS26
B	HIS81

site_id	MN3
Number of Residues	6
Details	MANGANESE-BOUND ACTIVE SITE ON CHAIN C. CATALYTIC REDOX CENTER.

Chain	Residue
C	MN206
C	HIS26
C	HIS81
C	ASP167
C	HIS171
C	OH207

site_id	MN4
Number of Residues	6
Details	MANGANESE-BOUND ACTIVE SITE ON CHAIN D. CATALYTIC REDOX CENTER.

Chain	Residue
D	MN206
D	HIS26
D	HIS81
D	ASP167
D	HIS171
D	OH207

Functional Information from PROSITE/UniProt

site_id	PS00088
Number of Residues	8
Details	SOD_MN Manganese and iron superoxide dismutases signature. DvWEHAYY

Chain	Residue	Details
A	ASP167-TYR174

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)