Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 440 |
| Chain | Residue |
| A | PRO56 |
| A | GLU57 |
| A | LYS67 |
| A | LYS70 |
| A | HOH701 |
| site_id | AC2 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD A 400 |
| Chain | Residue |
| A | VAL11 |
| A | GLY12 |
| A | SER13 |
| A | GLY14 |
| A | PRO15 |
| A | ALA16 |
| A | PHE34 |
| A | GLU35 |
| A | GLY36 |
| A | ILE37 |
| A | ALA38 |
| A | GLY41 |
| A | GLN42 |
| A | LEU43 |
| A | VAL49 |
| A | ASN51 |
| A | VAL84 |
| A | ALA111 |
| A | ILE112 |
| A | GLY113 |
| A | CYS138 |
| A | GLY285 |
| A | ASP286 |
| A | ARG293 |
| A | GLN294 |
| A | ALA295 |
| A | ALA298 |
| A | HOH506 |
| A | HOH507 |
| A | HOH516 |
| A | HOH519 |
| A | HOH522 |
| A | HOH524 |
| A | HOH526 |
| A | HOH545 |
| A | HOH585 |
| A | HOH630 |
| site_id | ACT |
| Number of Residues | 6 |
| Details | ACTIVE SITE. |
| Chain | Residue |
| A | CYS135 |
| A | CYS138 |
| A | ALA136 |
| A | ASP139 |
| A | GLY140 |
| A | GLU159 |
| site_id | FAD |
| Number of Residues | 16 |
| Details | FAD BINDING SITE. |
| Chain | Residue |
| A | PRO15 |
| A | ALA16 |
| A | GLY36 |
| A | GLY41 |
| A | THR46 |
| A | GLU50 |
| A | ASN51 |
| A | GLY61 |
| A | GLY113 |
| A | SER133 |
| A | ASP139 |
| A | GLY285 |
| A | ASP286 |
| A | GLY12 |
| A | SER13 |
| A | GLY14 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 23 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGaapiFrnkpLaVIGGGD |
| Chain | Residue | Details |
| A | CYS135-ASP155 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU50 | |
| A | GLN71 | |
| A | ILE79 | |
| A | PRO93 | |
| A | GLU126 | |
| A | ASP178 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| A | CYS135 | |
| A | CYS138 | |
| A | ASP139 | |
