1VAY

Crystal Structure of Uricase from Arthrobacter globiformis with inhibitor 8-azaxanthine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004846	molecular_function	urate oxidase activity
A	0006144	biological_process	purine nucleobase metabolic process
B	0004846	molecular_function	urate oxidase activity
B	0006144	biological_process	purine nucleobase metabolic process
C	0004846	molecular_function	urate oxidase activity
C	0006144	biological_process	purine nucleobase metabolic process
D	0004846	molecular_function	urate oxidase activity
D	0006144	biological_process	purine nucleobase metabolic process
E	0004846	molecular_function	urate oxidase activity
E	0006144	biological_process	purine nucleobase metabolic process
F	0004846	molecular_function	urate oxidase activity
F	0006144	biological_process	purine nucleobase metabolic process
G	0004846	molecular_function	urate oxidase activity
G	0006144	biological_process	purine nucleobase metabolic process
H	0004846	molecular_function	urate oxidase activity
H	0006144	biological_process	purine nucleobase metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AZA B 1301

Chain	Residue
B	PHE163
C	HOH349
B	ARG180
B	LEU222
B	GLN223
B	ASN249
B	HOH1388
C	TYR20
C	VAL64
C	THR67

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AZA D 1302

Chain	Residue
A	TYR20
A	VAL64
A	ALA66
A	THR67
D	PHE163
D	LEU174
D	ARG180
D	LEU222
D	GLN223
D	ASN249
D	HOH1335

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AZA B 1303

Chain	Residue
B	TYR20
B	VAL64
B	ALA66
B	THR67
B	HOH1373
C	PHE163
C	ARG180
C	ALA221
C	LEU222
C	GLN223
C	ASN249

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AZA A 1304

Chain	Residue
A	PHE163
A	LEU174
A	ARG180
A	ALA221
A	LEU222
A	GLN223
A	HOH1425
D	TYR20
D	VAL64
D	ALA66
D	THR67

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AZA H 1305

Chain	Residue
E	TYR20
E	VAL64
E	THR67
H	PHE163
H	LEU174
H	ARG180
H	ALA221
H	LEU222
H	GLN223
H	ASN249

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AZA G 1306

Chain	Residue
F	VAL64
F	ALA66
F	THR67
G	PHE163
G	LEU174
G	ARG180
G	ALA221
G	LEU222
G	GLN223
G	ASN249
G	HOH1428

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AZA F 1307

Chain	Residue
F	PHE163
F	ARG180
F	ALA221
F	LEU222
F	GLN223
F	ASN249
F	HOH1418
G	TYR20
G	VAL64
G	ALA66
G	THR67

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE AZA E 1308

Chain	Residue
E	PHE163
E	LEU174
E	ARG180
E	ALA221
E	LEU222
E	GLN223
E	ASN249
E	HOH1374
H	TYR20
H	VAL64
H	THR67
H	HOH1339

---

Functional Information from PROSITE/UniProt

site_id	PS00366
Number of Residues	28
Details	URICASE Uricase signature. LtVLKSTgSeFhgFprdkYttLqettdR

Chain	Residue	Details
A	LEU153-ARG180

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
A	ARG180
A	GLN223

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
B	ARG180
B	GLN223

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
C	ARG180
C	GLN223

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
D	ARG180
D	GLN223

---

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
E	ARG180
E	GLN223

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
F	ARG180
F	GLN223

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
G	ARG180
G	GLN223

---

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
H	ARG180
H	GLN223

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