Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1VA4

Pseudomonas fluorescens aryl esterase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004064	molecular_function	arylesterase activity
A	0004601	molecular_function	peroxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016787	molecular_function	hydrolase activity
A	0098869	biological_process	cellular oxidant detoxification
B	0003824	molecular_function	catalytic activity
B	0004064	molecular_function	arylesterase activity
B	0004601	molecular_function	peroxidase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016787	molecular_function	hydrolase activity
B	0098869	biological_process	cellular oxidant detoxification
C	0003824	molecular_function	catalytic activity
C	0004064	molecular_function	arylesterase activity
C	0004601	molecular_function	peroxidase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016787	molecular_function	hydrolase activity
C	0098869	biological_process	cellular oxidant detoxification
D	0003824	molecular_function	catalytic activity
D	0004064	molecular_function	arylesterase activity
D	0004601	molecular_function	peroxidase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016787	molecular_function	hydrolase activity
D	0098869	biological_process	cellular oxidant detoxification
E	0003824	molecular_function	catalytic activity
E	0004064	molecular_function	arylesterase activity
E	0004601	molecular_function	peroxidase activity
E	0016491	molecular_function	oxidoreductase activity
E	0016787	molecular_function	hydrolase activity
E	0098869	biological_process	cellular oxidant detoxification
F	0003824	molecular_function	catalytic activity
F	0004064	molecular_function	arylesterase activity
F	0004601	molecular_function	peroxidase activity
F	0016491	molecular_function	oxidoreductase activity
F	0016787	molecular_function	hydrolase activity
F	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 280

Chain	Residue
A	SER1
A	TYR12
A	LYS14
A	ASP15
A	HOH302
C	ASP61
C	GLN62

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 280

Chain	Residue
D	THR196
D	GLU200
D	HOH405
D	HOH492
D	ALA141
D	LYS144

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 280

Chain	Residue
B	ASP61
B	GLN62
C	SER1
C	TYR12
C	LYS14
C	ASP15
C	HOH613

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL D 281

Chain	Residue
D	SER1
D	TYR12
D	PHE13
D	LYS14
D	ASP15
D	HOH304
E	ASP61
E	GLN62

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 280

Chain	Residue
E	SER1
E	TYR12
E	LYS14
E	ASP15
E	HOH418
F	ASP61
F	GLN62

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F 280

Chain	Residue
D	ASP61
D	GLN62
F	SER1
F	TYR12
F	LYS14
F	ASP15
F	HOH383

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 281

Chain	Residue
A	ALA141
A	LYS144
A	THR196
A	ALA199
A	GLU200
A	HOH433

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 280

Chain	Residue
B	HIS257
B	ALA258
B	GLN259
B	GLN260
B	HOH435
B	HOH493

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 281

Chain	Residue
B	ALA141
B	LYS144
B	THR196
B	GLU200
B	HOH492
B	HOH506

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 281

Chain	Residue
C	LEU137
C	ALA141
C	LYS144
C	THR196
C	GLU200

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 281

Chain	Residue
E	LEU137
E	ALA141
E	LYS144
E	THR196
E	GLU200
E	HOH449

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL F 281

Chain	Residue
F	LYS144
F	GLU200
F	HOH388

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 282

Chain	Residue
A	ASP61
A	GLN62
B	SER1
B	TYR12
B	LYS14
B	ASP15
B	HOH327

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 282

Chain	Residue
D	TYR163
D	VAL175
D	GLN178
D	THR179
D	HOH311
D	HOH336

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL F 282

Chain	Residue
F	SER156
F	ASN159
F	GLN176
F	THR177
F	HOH364
F	HOH389

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 282

Chain	Residue
E	TYR163
E	GLN178
E	THR179
E	HOH348
E	HOH367
E	HOH482

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 282

Chain	Residue
A	TYR163
A	VAL175
A	GLN178
A	THR179
A	HOH354
A	HOH365

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 283

Chain	Residue
B	LEU30
B	TYR163
B	VAL175
B	GLN178
B	THR179
B	HOH373
B	HOH394

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 282

Chain	Residue
C	TYR163
C	VAL175
C	GLN178
C	THR179
C	HOH795
C	HOH1287
C	HOH1514

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F 283

Chain	Residue
F	TYR163
F	VAL175
F	GLN178
F	THR179
F	HOH352
F	HOH380
F	HOH407

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ACT_SITE: ACT_SITE => ECO:0000305\|PubMed:15213385

Chain	Residue	Details
A	MET95
D	MET95
D	GLN223
D	GLY252
E	MET95
E	GLN223
E	GLY252
F	MET95
F	GLN223
F	GLY252
A	GLN223
A	GLY252
B	MET95
B	GLN223
B	GLY252
C	MET95
C	GLN223
C	GLY252

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269\|PubMed:20112920, ECO:0007744\|PDB:3HI4

Chain	Residue	Details
A	LEU29
E	GLY96
F	LEU29
F	GLY96
A	GLY96
B	LEU29
B	GLY96
C	LEU29
C	GLY96
D	LEU29
D	GLY96
E	LEU29

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
A	HIS251
A	ASP222
A	SER94

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
B	HIS251
B	ASP222
B	SER94

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
C	HIS251
C	ASP222
C	SER94

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
D	HIS251
D	ASP222
D	SER94

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
E	HIS251
E	ASP222
E	SER94

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1azw

Chain	Residue	Details
F	HIS251
F	ASP222
F	SER94

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)