Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1V9S

Crystal structure of TT0130 protein from Thermus thermophilus HB8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0004845	molecular_function	uracil phosphoribosyltransferase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0006223	biological_process	uracil salvage
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0044206	biological_process	UMP salvage
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0004845	molecular_function	uracil phosphoribosyltransferase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0006223	biological_process	uracil salvage
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0044206	biological_process	UMP salvage
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0004845	molecular_function	uracil phosphoribosyltransferase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0006223	biological_process	uracil salvage
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0044206	biological_process	UMP salvage
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0004845	molecular_function	uracil phosphoribosyltransferase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0006223	biological_process	uracil salvage
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0044206	biological_process	UMP salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 509

Chain	Residue
C	GLY24
C	PRO25
C	LYS26
D	HIS93
D	ARG95
D	HOH536

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 510

Chain	Residue
D	ARG124
D	LYS69
D	LYS70
D	ARG95

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 511

Chain	Residue
A	GLY24
A	PRO25
A	LYS26
B	HIS93
B	ARG95
B	HOH543

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 512

Chain	Residue
B	LYS69
B	LYS70
B	ARG95
B	ARG124

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 513

Chain	Residue
A	LYS69
A	LYS70
A	ARG95
A	ARG124
A	SO4521
A	HOH557

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 514

Chain	Residue
A	ARG78
A	ALA79
A	GLY201

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 515

Chain	Residue
A	LYS70
A	HIS93
A	ARG95
A	HOH545
B	GLY24
B	PRO25
B	LYS26

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 516

Chain	Residue
A	TYR114
B	ARG78
B	TYR102
B	HOH533
B	HOH609
B	HOH610

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 517

Chain	Residue
A	MSE132
A	ALA134
A	THR135
A	GLY136
A	GLY137
A	SER138
A	ALA139

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 518

Chain	Residue
A	LYS147
A	HIS173
A	PRO174
A	ASP175
A	THR176
A	HOH571

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 519

Chain	Residue
B	LYS147
B	ASP172
B	HIS173
B	PRO174
B	ASP175
B	HOH568
B	HOH619

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 520

Chain	Residue
B	ARG186
B	ASN188
B	ASP189

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 521

Chain	Residue
A	ARG95
A	PRO119
A	SO4513
B	GLY206

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 522

Chain	Residue
C	LYS69
C	LYS70
C	ARG95
C	ARG124
C	HOH610

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 523

Chain	Residue
C	HIS93
C	ARG95
C	HOH554
D	GLY24
D	PRO25
D	LYS26

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 524

Chain	Residue
C	ARG78
C	LEU101
C	HOH558
C	HOH604
C	HOH606
D	TYR114

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 525

Chain	Residue
C	LYS147
C	HIS173
C	PRO174
C	ASP175
C	THR176
C	HOH631

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 526

Chain	Residue
A	ARG62
C	ARG186
C	ASN188
C	ASP189

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 527

Chain	Residue
D	GLY201
D	HOH602
C	TYR114
D	ARG78
D	ALA79

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 528

Chain	Residue
D	MSE132
D	ALA134
D	THR135
D	GLY136
D	GLY137
D	SER138

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 529

Chain	Residue
B	ARG62
D	ARG186
D	ASN188
D	ASP189

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 530

Chain	Residue
A	LYS89
C	LYS89
D	LYS89

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 531

Chain	Residue
D	LYS147
D	ASP172
D	HIS173
D	PRO174
D	ASP175

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01218","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
A	ASP199

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
B	ASP199
B	ARG103
B	SER107

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
C	ASP199
C	ARG103
C	SER107

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
D	ASP199

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)