Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1V9L

L-glutamate dehydrogenase from Pyrobaculum islandicum complexed with NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
A	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
A	0006103	biological_process	2-oxoglutarate metabolic process
A	0006520	biological_process	amino acid metabolic process
A	0006536	biological_process	glutamate metabolic process
A	0006538	biological_process	L-glutamate catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
A	0030554	molecular_function	adenyl nucleotide binding
A	0043168	molecular_function	anion binding
B	0000166	molecular_function	nucleotide binding
B	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
B	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
B	0006103	biological_process	2-oxoglutarate metabolic process
B	0006520	biological_process	amino acid metabolic process
B	0006536	biological_process	glutamate metabolic process
B	0006538	biological_process	L-glutamate catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
B	0030554	molecular_function	adenyl nucleotide binding
B	0043168	molecular_function	anion binding
C	0000166	molecular_function	nucleotide binding
C	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
C	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
C	0006103	biological_process	2-oxoglutarate metabolic process
C	0006520	biological_process	amino acid metabolic process
C	0006536	biological_process	glutamate metabolic process
C	0006538	biological_process	L-glutamate catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
C	0030554	molecular_function	adenyl nucleotide binding
C	0043168	molecular_function	anion binding
D	0000166	molecular_function	nucleotide binding
D	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
D	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
D	0006103	biological_process	2-oxoglutarate metabolic process
D	0006520	biological_process	amino acid metabolic process
D	0006536	biological_process	glutamate metabolic process
D	0006538	biological_process	L-glutamate catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
D	0030554	molecular_function	adenyl nucleotide binding
D	0043168	molecular_function	anion binding
E	0000166	molecular_function	nucleotide binding
E	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
E	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
E	0006103	biological_process	2-oxoglutarate metabolic process
E	0006520	biological_process	amino acid metabolic process
E	0006536	biological_process	glutamate metabolic process
E	0006538	biological_process	L-glutamate catabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
E	0030554	molecular_function	adenyl nucleotide binding
E	0043168	molecular_function	anion binding
F	0000166	molecular_function	nucleotide binding
F	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
F	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
F	0006103	biological_process	2-oxoglutarate metabolic process
F	0006520	biological_process	amino acid metabolic process
F	0006536	biological_process	glutamate metabolic process
F	0006538	biological_process	L-glutamate catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
F	0030554	molecular_function	adenyl nucleotide binding
F	0043168	molecular_function	anion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NAD A 430

Chain	Residue
A	THR189
A	ILE300
A	GLY320
A	ALA321
A	ASN322
A	ASN347
A	HOH431
A	GLN216
A	GLY217
A	GLY219
A	ASN220
A	VAL221
A	ASP241
A	ILE242
A	ALA299

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NAD B 1430

Chain	Residue
B	THR189
B	GLN216
B	GLY219
B	ASN220
B	VAL221
B	ASP241
B	ILE242
B	ALA299
B	ALA321
B	ASN322
B	ASN347
B	HOH1432

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NAD C 2430

Chain	Residue
C	THR189
C	GLY219
C	ASN220
C	VAL221
C	SER240
C	ASP241
C	ILE242
C	GLY265
C	ALA299
C	ILE300
C	ALA321
C	ASN322
C	ASN347

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NAD D 3430

Chain	Residue
D	THR189
D	GLN216
D	GLY219
D	ASN220
D	VAL221
D	ASP241
D	ILE242
D	GLY265
D	ALA298
D	ALA299
D	GLY320
D	ALA321
D	ASN322

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAD E 4430

Chain	Residue
E	THR189
E	GLY217
E	GLY219
E	ASN220
E	VAL221
E	ASP241
E	ILE242
E	ALA299
E	ILE300
E	GLY320
E	ALA321
E	ASN322
E	ASN347
E	HOH4431

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NAD F 5430

Chain	Residue
F	GLY219
F	ASN220
F	VAL221
F	ASP241
F	ILE242
F	ALA298
F	ALA299
F	ILE300
F	GLY320
F	ALA321
F	ASN322

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
A	ASP145
A	LYS105

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
B	ASP145
B	LYS105

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
C	ASP145
C	LYS105

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
D	ASP145
D	LYS105

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
E	ASP145
E	LYS105

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
F	ASP145
F	LYS105

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)