1V9I

Crystal Structure Analysis of the site specific mutant (Q253C) of bovine carbonic anhydrase II

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0004089	molecular_function	carbonate dehydratase activity
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0006730	biological_process	one-carbon metabolic process
C	0008270	molecular_function	zinc ion binding
C	0015670	biological_process	carbon dioxide transport
C	0016829	molecular_function	lyase activity
C	0018820	molecular_function	cyanamide hydratase activity
C	0038166	biological_process	angiotensin-activated signaling pathway
C	0044070	biological_process	regulation of monoatomic anion transport
C	0045177	cellular_component	apical part of cell
C	0046872	molecular_function	metal ion binding
C	0051453	biological_process	regulation of intracellular pH
C	2001150	biological_process	positive regulation of dipeptide transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 262

Chain	Residue
C	HIS95
C	HIS97
C	HIS120
C	THR199

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Functional Information from PROSITE/UniProt

site_id	PS00162
Number of Residues	17
Details	ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVdrkkYaaELHLV

Chain	Residue	Details
C	SER106-VAL122

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:P00918

Chain	Residue	Details
C	SER66

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15039588

Chain	Residue	Details
C	PHE96
C	TRP98
C	LEU121

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P00918

Chain	Residue	Details
C	THR200

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site_id	SWS_FT_FI4
Number of Residues	3
Details	SITE: Fine-tunes the proton-transfer properties of H-64 => ECO:0000250|UniProtKB:P00918

Chain	Residue	Details
C	GLY9
C	GLY64
C	VAL69

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P27139

Chain	Residue	Details
C	HIS4

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site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P00918

Chain	Residue	Details
C	ILE167
C	THR174

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1ca2

Chain	Residue	Details
C	THR199
C	HIS65

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