1V5H
Crystal Structure of Human Cytoglobin (Ferric Form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001666 | biological_process | response to hypoxia |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0004784 | molecular_function | superoxide dismutase activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0010764 | biological_process | negative regulation of fibroblast migration |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016607 | cellular_component | nuclear speck |
| A | 0019395 | biological_process | fatty acid oxidation |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0032966 | biological_process | negative regulation of collagen biosynthetic process |
| A | 0043005 | cellular_component | neuron projection |
| A | 0043025 | cellular_component | neuronal cell body |
| A | 0046209 | biological_process | nitric oxide metabolic process |
| A | 0046210 | biological_process | nitric oxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047888 | molecular_function | fatty acid peroxidase activity |
| A | 0070025 | molecular_function | carbon monoxide binding |
| A | 0098809 | molecular_function | nitrite reductase activity |
| A | 0141118 | molecular_function | nitric oxide dioxygenase activity, heme protein as donor |
| A | 2000490 | biological_process | negative regulation of hepatic stellate cell activation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 191 |
| Chain | Residue |
| A | SER55 |
| A | LEU89 |
| A | HIS113 |
| A | LYS116 |
| A | HIS117 |
| A | VAL119 |
| A | TYR123 |
| A | PHE124 |
| A | HOH201 |
| A | HOH210 |
| A | ALA56 |
| A | TYR59 |
| A | PHE60 |
| A | GLN77 |
| A | HIS81 |
| A | ARG84 |
| A | VAL85 |
| A | ALA88 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"distal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15044115","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15095869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15165856","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16699195","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1URV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1URY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1V5H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DC3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15044115","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15095869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15165856","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16699195","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1URV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1URY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1V5H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DC3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
