1V1B
2-KETO-3-DEOXYGLUCONATE KINASE FROM THERMUS THERMOPHILUS WITH BOUND ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008673 | molecular_function | 2-dehydro-3-deoxygluconokinase activity |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008673 | molecular_function | 2-dehydro-3-deoxygluconokinase activity |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008673 | molecular_function | 2-dehydro-3-deoxygluconokinase activity |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| C | 0046835 | biological_process | carbohydrate phosphorylation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008673 | molecular_function | 2-dehydro-3-deoxygluconokinase activity |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
| D | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| D | 0046835 | biological_process | carbohydrate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP A1301 |
| Chain | Residue |
| A | ASN165 |
| A | GLY248 |
| A | ALA249 |
| A | GLY250 |
| A | ASP251 |
| A | PHE253 |
| A | ASN275 |
| A | ALA279 |
| A | SER193 |
| A | LYS219 |
| A | GLY221 |
| A | GLY224 |
| A | ALA238 |
| A | PHE239 |
| A | VAL241 |
| A | PRO246 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ATP B1301 |
| Chain | Residue |
| B | LYS219 |
| B | GLY221 |
| B | GLY224 |
| B | ALA238 |
| B | PHE239 |
| B | VAL241 |
| B | PRO246 |
| B | GLY248 |
| B | ALA249 |
| B | GLY250 |
| B | ASP251 |
| B | PHE253 |
| B | ASN275 |
| B | ALA279 |
| B | HOH2030 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ATP C1301 |
| Chain | Residue |
| C | SER193 |
| C | LYS219 |
| C | GLY221 |
| C | GLY224 |
| C | ALA238 |
| C | PHE239 |
| C | VAL241 |
| C | PRO246 |
| C | GLY248 |
| C | ALA249 |
| C | GLY250 |
| C | ASP251 |
| C | PHE253 |
| C | ASN275 |
| C | ALA279 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP D1301 |
| Chain | Residue |
| D | LYS219 |
| D | GLY221 |
| D | GLY224 |
| D | ALA238 |
| D | PHE239 |
| D | VAL241 |
| D | PRO246 |
| D | GLY248 |
| D | ALA249 |
| D | GLY250 |
| D | ASP251 |
| D | PHE253 |
| D | ASN275 |
| D | ALA279 |
| D | HOH2018 |
| D | HOH2019 |
Functional Information from PROSITE/UniProt
| site_id | PS00584 |
| Number of Residues | 14 |
| Details | PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DPvGAGDafaAGYL |
| Chain | Residue | Details |
| A | ASP245-LEU258 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:15210349 |
| Chain | Residue | Details |
| A | ASP251 | |
| B | ASP251 | |
| C | ASP251 | |
| D | ASP251 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15210349 |
| Chain | Residue | Details |
| A | GLY34 | |
| B | GLY34 | |
| B | TYR103 | |
| B | ARG167 | |
| B | SER193 | |
| B | LYS219 | |
| B | GLY248 | |
| B | ASP251 | |
| B | ASN275 | |
| B | ASP287 | |
| C | GLY34 | |
| A | TYR103 | |
| C | TYR103 | |
| C | ARG167 | |
| C | SER193 | |
| C | LYS219 | |
| C | GLY248 | |
| C | ASP251 | |
| C | ASN275 | |
| C | ASP287 | |
| D | GLY34 | |
| D | TYR103 | |
| A | ARG167 | |
| D | ARG167 | |
| D | SER193 | |
| D | LYS219 | |
| D | GLY248 | |
| D | ASP251 | |
| D | ASN275 | |
| D | ASP287 | |
| A | SER193 | |
| A | LYS219 | |
| A | GLY248 | |
| A | ASP251 | |
| A | ASN275 | |
| A | ASP287 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q97U29 |
| Chain | Residue | Details |
| A | TYR89 | |
| A | ASN165 | |
| B | TYR89 | |
| B | ASN165 | |
| C | TYR89 | |
| C | ASN165 | |
| D | TYR89 | |
| D | ASN165 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | GLY248 | |
| A | ALA249 | |
| A | ASP251 | |
| A | GLY250 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| B | ARG100 | |
| B | ASP251 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| C | ARG100 | |
| C | ASP251 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| D | ARG100 | |
| D | ASP251 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| B | GLY248 | |
| B | ALA249 | |
| B | ASP251 | |
| B | GLY250 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| C | GLY248 | |
| C | ALA249 | |
| C | ASP251 | |
| C | GLY250 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| D | GLY248 | |
| D | ALA249 | |
| D | ASP251 | |
| D | GLY250 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | GLY248 | |
| A | LYS219 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| B | GLY248 | |
| B | LYS219 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| C | GLY248 | |
| C | LYS219 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| D | GLY248 | |
| D | LYS219 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | ARG100 | |
| A | ASP251 |
