1V1B

2-KETO-3-DEOXYGLUCONATE KINASE FROM THERMUS THERMOPHILUS WITH BOUND ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0008673	molecular_function	2-dehydro-3-deoxygluconokinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0046835	biological_process	carbohydrate phosphorylation
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0008673	molecular_function	2-dehydro-3-deoxygluconokinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0046835	biological_process	carbohydrate phosphorylation
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0008673	molecular_function	2-dehydro-3-deoxygluconokinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0046835	biological_process	carbohydrate phosphorylation
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0008673	molecular_function	2-dehydro-3-deoxygluconokinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0046835	biological_process	carbohydrate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ATP A1301

Chain	Residue
A	ASN165
A	GLY248
A	ALA249
A	GLY250
A	ASP251
A	PHE253
A	ASN275
A	ALA279
A	SER193
A	LYS219
A	GLY221
A	GLY224
A	ALA238
A	PHE239
A	VAL241
A	PRO246

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ATP B1301

Chain	Residue
B	LYS219
B	GLY221
B	GLY224
B	ALA238
B	PHE239
B	VAL241
B	PRO246
B	GLY248
B	ALA249
B	GLY250
B	ASP251
B	PHE253
B	ASN275
B	ALA279
B	HOH2030

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ATP C1301

Chain	Residue
C	SER193
C	LYS219
C	GLY221
C	GLY224
C	ALA238
C	PHE239
C	VAL241
C	PRO246
C	GLY248
C	ALA249
C	GLY250
C	ASP251
C	PHE253
C	ASN275
C	ALA279

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ATP D1301

Chain	Residue
D	LYS219
D	GLY221
D	GLY224
D	ALA238
D	PHE239
D	VAL241
D	PRO246
D	GLY248
D	ALA249
D	GLY250
D	ASP251
D	PHE253
D	ASN275
D	ALA279
D	HOH2018
D	HOH2019

---

Functional Information from PROSITE/UniProt

site_id	PS00584
Number of Residues	14
Details	PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DPvGAGDafaAGYL

Chain	Residue	Details
A	ASP245-LEU258

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"15210349","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15210349","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q97U29","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
A	GLY248
A	ALA249
A	ASP251
A	GLY250

---

site_id	CSA10
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
B	ARG100
B	ASP251

---

site_id	CSA11
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
C	ARG100
C	ASP251

---

site_id	CSA12
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
D	ARG100
D	ASP251

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
B	GLY248
B	ALA249
B	ASP251
B	GLY250

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
C	GLY248
C	ALA249
C	ASP251
C	GLY250

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
D	GLY248
D	ALA249
D	ASP251
D	GLY250

---

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
A	GLY248
A	LYS219

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
B	GLY248
B	LYS219

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
C	GLY248
C	LYS219

---

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
D	GLY248
D	LYS219

---

site_id	CSA9
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

Chain	Residue	Details
A	ARG100
A	ASP251

---