1UXQ
Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008886 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity |
| A | 0008911 | molecular_function | lactaldehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:15288789 |
| Chain | Residue | Details |
| A | GLU263 | |
| A | CYS297 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15288789, ECO:0007744|PDB:1UXR |
| Chain | Residue | Details |
| A | ARG72 | |
| A | ARG79 | |
| A | TYR184 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15288789, ECO:0007744|PDB:1UXU |
| Chain | Residue | Details |
| A | GLY134 | |
| A | ARG154 | |
| A | ASN168 | |
| A | ARG296 | |
| A | HIS455 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11842090, ECO:0000269|PubMed:15288789, ECO:0007744|PDB:1KY8, ECO:0007744|PDB:1UXN, ECO:0007744|PDB:1UXP, ECO:0007744|PDB:1UXQ, ECO:0007744|PDB:1UXR, ECO:0007744|PDB:1UXU, ECO:0007744|PDB:1UXV |
| Chain | Residue | Details |
| A | THR165 | |
| A | GLY224 | |
| A | GLU228 | |
| A | SER244 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15288789, ECO:0007744|PDB:1UXT |
| Chain | Residue | Details |
| A | LYS191 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11842090, ECO:0000269|PubMed:15288789, ECO:0007744|PDB:1KY8, ECO:0007744|PDB:1UXN, ECO:0007744|PDB:1UXP, ECO:0007744|PDB:1UXQ, ECO:0007744|PDB:1UXR, ECO:0007744|PDB:1UXV |
| Chain | Residue | Details |
| A | GLY265 | |
| A | GLU395 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| A | CYS297 | |
| A | GLU263 | |
| A | ASN168 |
