1UUZ

IVY:A NEW FAMILY OF PROTEIN

Replaces:  1HKE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042597	cellular_component	periplasmic space
A	0043086	biological_process	negative regulation of catalytic activity
B	0042597	cellular_component	periplasmic space
B	0043086	biological_process	negative regulation of catalytic activity
C	0003796	molecular_function	lysozyme activity
C	0003824	molecular_function	catalytic activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0016231	molecular_function	beta-N-acetylglucosaminidase activity
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0050829	biological_process	defense response to Gram-negative bacterium
C	0050830	biological_process	defense response to Gram-positive bacterium
C	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
D	0003796	molecular_function	lysozyme activity
D	0003824	molecular_function	catalytic activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0016231	molecular_function	beta-N-acetylglucosaminidase activity
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0016998	biological_process	cell wall macromolecule catabolic process
D	0031640	biological_process	killing of cells of another organism
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0050829	biological_process	defense response to Gram-negative bacterium
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
C	CYS76-CYS94

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Site: {"description":"Important for lysozyme inhibition","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	256
Details	Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
C	GLU35
C	ASP52

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
D	GLU35
D	ASP52

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site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
C	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	ASN46
C	ASP48
C	SER50
C	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
C	ASN59

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site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
D	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
D	ASN46
D	ASP48
D	SER50
D	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
D	ASN59

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