Functional Information from GO Data
| Chain | GOid | namespace | contents |
| M | 0004252 | molecular_function | serine-type endopeptidase activity |
| M | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PRA M 246 |
| Chain | Residue |
| M | TYR20 |
| M | ASP189 |
| M | SER190 |
| M | SER195 |
| M | SER214 |
| M | TRP215 |
| M | GLY216 |
| M | HOH2069 |
| M | HOH2072 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA M 247 |
| Chain | Residue |
| M | GLU70 |
| M | ASN72 |
| M | VAL75 |
| M | GLU77 |
| M | GLU80 |
| M | HOH2018 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MPD M 248 |
| Chain | Residue |
| M | CYS128 |
| M | ALA129 |
| M | PHE181 |
| M | HOH2073 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| M | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| M | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 219 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for specificity","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | ASP102 | |
| M | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | SER195 | |
| M | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | SER195 | |
| M | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | ASP102 | |
| M | SER195 | |
| M | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | ASP102 | |
| M | SER195 | |
| M | GLY193 | |
| M | HIS57 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| M | ASP102 | |
| M | SER195 | |
| M | HIS57 | |
| M | GLY196 | |
