1UPX
The crystal structure of the Hybrid Cluster Protein from Desulfovibrio desulfuricans containing molecules in the oxidized and reduced states.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016661 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050418 | molecular_function | hydroxylamine reductase activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016661 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors |
| B | 0042542 | biological_process | response to hydrogen peroxide |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050418 | molecular_function | hydroxylamine reductase activity |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SF4 A1544 |
| Chain | Residue |
| A | CYS6 |
| A | LYS26 |
| A | THR75 |
| A | TYR7 |
| A | GLN8 |
| A | CYS9 |
| A | THR12 |
| A | CYS18 |
| A | GLY22 |
| A | VAL23 |
| A | CYS24 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SF3 A1545 |
| Chain | Residue |
| A | HIS240 |
| A | GLU264 |
| A | TRP288 |
| A | CYS308 |
| A | CYS399 |
| A | CYS427 |
| A | CYS452 |
| A | GLU487 |
| A | FSO1546 |
| A | HOH2841 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FSO A1546 |
| Chain | Residue |
| A | HIS240 |
| A | SER263 |
| A | GLU264 |
| A | ASN307 |
| A | CYS308 |
| A | CYS399 |
| A | CYS427 |
| A | CYS452 |
| A | GLU487 |
| A | LYS489 |
| A | ALA490 |
| A | SF31545 |
| A | HOH2521 |
| A | HOH2841 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SF4 B1544 |
| Chain | Residue |
| B | CYS6 |
| B | TYR7 |
| B | GLN8 |
| B | CYS9 |
| B | THR12 |
| B | CYS18 |
| B | GLY22 |
| B | VAL23 |
| B | CYS24 |
| B | LYS26 |
| B | THR75 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SF3 B1545 |
| Chain | Residue |
| B | HIS240 |
| B | GLU264 |
| B | TRP288 |
| B | CYS308 |
| B | CYS399 |
| B | CYS427 |
| B | CYS452 |
| B | GLU487 |
| B | FSO1546 |
| B | HOH2834 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE FSO B1546 |
| Chain | Residue |
| B | HIS240 |
| B | SER263 |
| B | GLU264 |
| B | TRP288 |
| B | ASN307 |
| B | CYS308 |
| B | CYS399 |
| B | CYS427 |
| B | CYS452 |
| B | GLU487 |
| B | LYS489 |
| B | ALA490 |
| B | SF31545 |
| B | HOH2521 |
| B | HOH2834 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES B1547 |
| Chain | Residue |
| A | ILE227 |
| A | SER362 |
| A | GLU364 |
| A | LYS434 |
| B | LYS313 |
| B | ASP314 |
| B | HOH2560 |
| B | HOH2836 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12764602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14646063","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"via persulfide group","evidences":[{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12764602","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14646063","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Cysteine persulfide; in oxidized form","evidences":[{"source":"PubMed","id":"11941509","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
