1UOE
Crystal structure of the dihydroxyacetone kinase from E. coli in complex with glyceraldehyde
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004371 | molecular_function | glycerone kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006071 | biological_process | glycerol metabolic process |
| A | 0006090 | biological_process | pyruvate metabolic process |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0042182 | biological_process | ketone catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046365 | biological_process | monosaccharide catabolic process |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0047324 | molecular_function | phosphoenolpyruvate-glycerone phosphotransferase activity |
| A | 0061610 | biological_process | glycerol to glycerone phosphate metabolic process |
| A | 1990234 | cellular_component | transferase complex |
| B | 0004371 | molecular_function | glycerone kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006071 | biological_process | glycerol metabolic process |
| B | 0006090 | biological_process | pyruvate metabolic process |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0042182 | biological_process | ketone catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046365 | biological_process | monosaccharide catabolic process |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0047324 | molecular_function | phosphoenolpyruvate-glycerone phosphotransferase activity |
| B | 0061610 | biological_process | glycerol to glycerone phosphate metabolic process |
| B | 1990234 | cellular_component | transferase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1370 |
| Chain | Residue |
| A | HIS33 |
| A | PRO34 |
| A | SER35 |
| A | HOH2230 |
| A | HOH2231 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1370 |
| Chain | Residue |
| B | HOH2247 |
| B | HIS33 |
| B | PRO34 |
| B | SER35 |
| B | HOH2246 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1369 |
| Chain | Residue |
| A | GLY62 |
| A | GLY63 |
| A | HIS66 |
| A | PHE88 |
| A | SER90 |
| A | TYR116 |
| A | ASP119 |
| A | HIS230 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B1369 |
| Chain | Residue |
| B | GLY62 |
| B | GLY63 |
| B | HIS66 |
| B | PHE88 |
| B | THR89 |
| B | SER90 |
| B | TYR116 |
| B | ASP119 |
| B | HIS230 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21209328 |
| Chain | Residue | Details |
| A | HIS66 | |
| B | HIS66 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Tele-hemiaminal-histidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00814, ECO:0000269|PubMed:12813127, ECO:0000269|PubMed:15476397, ECO:0000269|PubMed:21209328, ECO:0007744|PDB:1OI2, ECO:0007744|PDB:1UOD, ECO:0007744|PDB:1UOE, ECO:0007744|PDB:3PNK, ECO:0007744|PDB:3PNL, ECO:0007744|PDB:3PNQ |
| Chain | Residue | Details |
| A | ASP220 | |
| B | ASP220 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12813127, ECO:0000269|PubMed:15476397, ECO:0000269|PubMed:21209328, ECO:0007744|PDB:1OI2, ECO:0007744|PDB:1UOD, ECO:0007744|PDB:1UOE, ECO:0007744|PDB:3PNK, ECO:0007744|PDB:3PNL, ECO:0007744|PDB:3PNQ |
| Chain | Residue | Details |
| B | GLY63 | |
| B | ASP119 | |
| A | GLY63 | |
| A | ASP119 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12813127, ECO:0000269|PubMed:21209328, ECO:0007744|PDB:1OI2, ECO:0007744|PDB:3PNK, ECO:0007744|PDB:3PNL, ECO:0007744|PDB:3PNQ |
| Chain | Residue | Details |
| A | LYS114 | |
| B | LYS114 |
