1UN6

THE CRYSTAL STRUCTURE OF A ZINC FINGER - RNA COMPLEX REVEALS TWO MODES OF MOLECULAR RECOGNITION

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 204

Chain	Residue
B	CYS107
B	CYS112
B	HIS125
B	HIS129

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 205

Chain	Residue
B	CYS137
B	CYS142
B	HIS155
B	HIS159

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 206

Chain	Residue
B	CYS170
B	HIS183
B	HIS188
B	CYS164

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 306

Chain	Residue
B	CYS164
B	ASP168
B	CYS170

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 307

Chain	Residue
B	PRO163
B	LYS165

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 308

Chain	Residue
B	CYS137
B	HIS139
B	CYS142

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 204

Chain	Residue
C	CYS107
C	CYS112
C	HIS125
C	HIS129

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 205

Chain	Residue
C	CYS137
C	CYS142
C	HIS155
C	HIS159

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 206

Chain	Residue
C	CYS164
C	CYS170
C	HIS183
C	HIS188

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 342

Chain	Residue
E	G7

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 344

Chain	Residue
C	CYS137
C	HIS139
C	CYS142

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 205

Chain	Residue
D	CYS137
D	CYS142
D	HIS155
D	HIS159

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 206

Chain	Residue
D	CYS164
D	CYS170
D	HIS183
D	HIS188

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 341

Chain	Residue
E	G113

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 343

Chain	Residue
E	G97
E	G98

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 302

Chain	Residue
F	G98

---

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 303

Chain	Residue
F	G114

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 304

Chain	Residue
F	G110

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 305

Chain	Residue
F	G70
F	G71

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 309

Chain	Residue
F	G66
F	C67
F	G108
F	U109

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. ChfenCgkaFkkhnqlkvHqfs..H

Chain	Residue	Details
B	CYS107-HIS129
B	CYS137-HIS159

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Zinc finger: {"description":"C2H2-type 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	72
Details	Zinc finger: {"description":"C2H2-type 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	78
Details	Zinc finger: {"description":"C2H2-type 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---