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1UMY

BHMT from rat liver

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006577biological_processamino-acid betaine metabolic process
A0006579biological_processamino-acid betaine catabolic process
A0008168molecular_functionmethyltransferase activity
A0008172molecular_functionS-methyltransferase activity
A0008270molecular_functionzinc ion binding
A0009086biological_processmethionine biosynthetic process
A0010243biological_processresponse to organonitrogen compound
A0016740molecular_functiontransferase activity
A0032259biological_processmethylation
A0032991cellular_componentprotein-containing complex
A0042802molecular_functionidentical protein binding
A0044877molecular_functionprotein-containing complex binding
A0046500biological_processS-adenosylmethionine metabolic process
A0046872molecular_functionmetal ion binding
A0047150molecular_functionbetaine-homocysteine S-methyltransferase activity
A0070062cellular_componentextracellular exosome
A0071266biological_process'de novo' L-methionine biosynthetic process
A0071267biological_processL-methionine salvage
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006577biological_processamino-acid betaine metabolic process
B0006579biological_processamino-acid betaine catabolic process
B0008168molecular_functionmethyltransferase activity
B0008172molecular_functionS-methyltransferase activity
B0008270molecular_functionzinc ion binding
B0009086biological_processmethionine biosynthetic process
B0010243biological_processresponse to organonitrogen compound
B0016740molecular_functiontransferase activity
B0032259biological_processmethylation
B0032991cellular_componentprotein-containing complex
B0042802molecular_functionidentical protein binding
B0044877molecular_functionprotein-containing complex binding
B0046500biological_processS-adenosylmethionine metabolic process
B0046872molecular_functionmetal ion binding
B0047150molecular_functionbetaine-homocysteine S-methyltransferase activity
B0070062cellular_componentextracellular exosome
B0071266biological_process'de novo' L-methionine biosynthetic process
B0071267biological_processL-methionine salvage
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006577biological_processamino-acid betaine metabolic process
C0006579biological_processamino-acid betaine catabolic process
C0008168molecular_functionmethyltransferase activity
C0008172molecular_functionS-methyltransferase activity
C0008270molecular_functionzinc ion binding
C0009086biological_processmethionine biosynthetic process
C0010243biological_processresponse to organonitrogen compound
C0016740molecular_functiontransferase activity
C0032259biological_processmethylation
C0032991cellular_componentprotein-containing complex
C0042802molecular_functionidentical protein binding
C0044877molecular_functionprotein-containing complex binding
C0046500biological_processS-adenosylmethionine metabolic process
C0046872molecular_functionmetal ion binding
C0047150molecular_functionbetaine-homocysteine S-methyltransferase activity
C0070062cellular_componentextracellular exosome
C0071266biological_process'de novo' L-methionine biosynthetic process
C0071267biological_processL-methionine salvage
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006577biological_processamino-acid betaine metabolic process
D0006579biological_processamino-acid betaine catabolic process
D0008168molecular_functionmethyltransferase activity
D0008172molecular_functionS-methyltransferase activity
D0008270molecular_functionzinc ion binding
D0009086biological_processmethionine biosynthetic process
D0010243biological_processresponse to organonitrogen compound
D0016740molecular_functiontransferase activity
D0032259biological_processmethylation
D0032991cellular_componentprotein-containing complex
D0042802molecular_functionidentical protein binding
D0044877molecular_functionprotein-containing complex binding
D0046500biological_processS-adenosylmethionine metabolic process
D0046872molecular_functionmetal ion binding
D0047150molecular_functionbetaine-homocysteine S-methyltransferase activity
D0070062cellular_componentextracellular exosome
D0071266biological_process'de novo' L-methionine biosynthetic process
D0071267biological_processL-methionine salvage
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A1399
ChainResidue
ATYR160
ACYS217
ACYS299
ACYS300

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B1399
ChainResidue
BTYR160
BCYS217
BCYS299
BCYS300

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN C1406
ChainResidue
CCYS217
CCYS299
CCYS300
CHOH2107
CTYR160

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN D1405
ChainResidue
DTYR160
DCYS217
DCYS299
DCYS300

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q93088, ECO:0000255|PROSITE-ProRule:PRU00333
ChainResidueDetails
ACYS217
ACYS299
ACYS300
BCYS217
BCYS299
BCYS300
CCYS217
CCYS299
CCYS300
DCYS217
DCYS299
DCYS300

site_idSWS_FT_FI2
Number of Residues28
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O35490
ChainResidueDetails
ALYS40
ALYS93
ALYS98
ALYS232
ALYS241
ALYS340
ALYS377
BLYS40
BLYS93
BLYS98
BLYS232
BLYS241
BLYS340
BLYS377
CLYS40
CLYS93
CLYS98
CLYS232
CLYS241
CLYS340
CLYS377
DLYS40
DLYS93
DLYS98
DLYS232
DLYS241
DLYS340
DLYS377

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ASER330
BSER330
CSER330
DSER330

218500

PDB entries from 2024-04-17

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