1UMY

BHMT from rat liver

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006579	biological_process	amino-acid betaine catabolic process
A	0008168	molecular_function	methyltransferase activity
A	0008270	molecular_function	zinc ion binding
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0044877	molecular_function	protein-containing complex binding
A	0047150	molecular_function	betaine-homocysteine S-methyltransferase activity
A	0071267	biological_process	L-methionine salvage
A	0097305	biological_process	response to alcohol
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0006579	biological_process	amino-acid betaine catabolic process
B	0008168	molecular_function	methyltransferase activity
B	0008270	molecular_function	zinc ion binding
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0044877	molecular_function	protein-containing complex binding
B	0047150	molecular_function	betaine-homocysteine S-methyltransferase activity
B	0071267	biological_process	L-methionine salvage
B	0097305	biological_process	response to alcohol
C	0005634	cellular_component	nucleus
C	0005829	cellular_component	cytosol
C	0006579	biological_process	amino-acid betaine catabolic process
C	0008168	molecular_function	methyltransferase activity
C	0008270	molecular_function	zinc ion binding
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0044877	molecular_function	protein-containing complex binding
C	0047150	molecular_function	betaine-homocysteine S-methyltransferase activity
C	0071267	biological_process	L-methionine salvage
C	0097305	biological_process	response to alcohol
D	0005634	cellular_component	nucleus
D	0005829	cellular_component	cytosol
D	0006579	biological_process	amino-acid betaine catabolic process
D	0008168	molecular_function	methyltransferase activity
D	0008270	molecular_function	zinc ion binding
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0044877	molecular_function	protein-containing complex binding
D	0047150	molecular_function	betaine-homocysteine S-methyltransferase activity
D	0071267	biological_process	L-methionine salvage
D	0097305	biological_process	response to alcohol

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A1399

Chain	Residue
A	TYR160
A	CYS217
A	CYS299
A	CYS300

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B1399

Chain	Residue
B	TYR160
B	CYS217
B	CYS299
B	CYS300

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C1406

Chain	Residue
C	CYS217
C	CYS299
C	CYS300
C	HOH2107
C	TYR160

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D1405

Chain	Residue
D	TYR160
D	CYS217
D	CYS299
D	CYS300

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q93088","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00333","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	26
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"O35490","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---