Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003863 | molecular_function | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity |
A | 0005515 | molecular_function | protein binding |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
A | 0046872 | molecular_function | metal ion binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0003863 | molecular_function | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity |
B | 0005515 | molecular_function | protein binding |
B | 0016491 | molecular_function | oxidoreductase activity |
C | 0003863 | molecular_function | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity |
C | 0005515 | molecular_function | protein binding |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
C | 0046872 | molecular_function | metal ion binding |
D | 0003824 | molecular_function | catalytic activity |
D | 0003863 | molecular_function | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity |
D | 0005515 | molecular_function | protein binding |
D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 1401 |
Chain | Residue |
A | ASP175 |
A | ASN204 |
A | TYR206 |
A | TPP1402 |
A | HOH1428 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG C 2401 |
Chain | Residue |
C | HOH2430 |
C | ASP175 |
C | ASN204 |
C | TYR206 |
C | TPP2402 |
site_id | AC3 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE TPP A 1402 |
Chain | Residue |
A | TYR94 |
A | TYR95 |
A | ARG96 |
A | SER144 |
A | PRO145 |
A | ILE146 |
A | GLY174 |
A | ASP175 |
A | GLY176 |
A | ALA177 |
A | GLU180 |
A | ASN204 |
A | TYR206 |
A | ALA207 |
A | ILE208 |
A | HIS273 |
A | MG1401 |
A | HOH1405 |
A | HOH1410 |
A | HOH1428 |
D | GLU29 |
D | LEU58 |
D | GLU60 |
D | GLN82 |
D | TYR86 |
D | 4MV1403 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE 4MV D 1403 |
Chain | Residue |
A | TYR95 |
A | MET128 |
A | HIS131 |
A | TPP1402 |
A | HOH1575 |
D | PHE83 |
D | TYR86 |
D | HIS128 |
D | HOH1520 |
site_id | AC5 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE TPP C 2402 |
Chain | Residue |
B | GLU29 |
B | LEU58 |
B | GLU60 |
B | GLN82 |
B | TYR86 |
C | TYR94 |
C | TYR95 |
C | ARG96 |
C | SER144 |
C | PRO145 |
C | ILE146 |
C | GLY174 |
C | ASP175 |
C | GLY176 |
C | ALA177 |
C | GLU180 |
C | ASN204 |
C | TYR206 |
C | ALA207 |
C | ILE208 |
C | HIS273 |
C | MG2401 |
C | HOH2405 |
C | HOH2422 |
C | HOH2430 |
Functional Information from PROSITE/UniProt
site_id | PS00014 |
Number of Residues | 4 |
Details | ER_TARGET Endoplasmic reticulum targeting sequence. KEEL |
Chain | Residue | Details |
A | LYS364-LEU367 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000305 |
Chain | Residue | Details |
B | HIS129 | |
A | HIS273 | |
C | PHE66 | |
C | TYR94 | |
C | TYR95 | |
C | MET128 | |
C | SER144 | |
C | GLY174 | |
C | ASP175 | |
C | ASN204 | |
C | TYR206 | |
D | HIS129 | |
C | HIS273 | |
A | TYR95 | |
A | MET128 | |
A | SER144 | |
A | GLY174 | |
A | ASP175 | |
A | ASN204 | |
A | TYR206 | |
Chain | Residue | Details |
B | GLU29 | |
B | GLN82 | |
D | GLU29 | |
D | GLN82 | |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: |
Chain | Residue | Details |
B | LEU58 | |
B | PHE83 | |
B | TYR86 | |
D | LEU58 | |
D | PHE83 | |
D | TYR86 | |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000305 |
Chain | Residue | Details |
B | HIS129 | |
D | HIS129 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
C | HIS273 | |
B | GLU60 | |
B | HIS129 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS273 | |
D | GLU60 | |
D | HIS129 | |