1UM0
Crystal structure of chorismate synthase complexed with FMN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004107 | molecular_function | chorismate synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016829 | molecular_function | lyase activity |
| B | 0004107 | molecular_function | chorismate synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016829 | molecular_function | lyase activity |
| C | 0004107 | molecular_function | chorismate synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0010181 | molecular_function | FMN binding |
| C | 0016829 | molecular_function | lyase activity |
| D | 0004107 | molecular_function | chorismate synthase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0010181 | molecular_function | FMN binding |
| D | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN A 1400 |
| Chain | Residue |
| A | SER103 |
| A | PRO299 |
| A | SER300 |
| A | ILE327 |
| A | ARG330 |
| A | HOH1420 |
| A | HOH1432 |
| A | HOH1436 |
| A | HOH1529 |
| D | LEU280 |
| D | GLY281 |
| A | HIS104 |
| A | ARG123 |
| A | SER125 |
| A | LEU240 |
| A | ASN241 |
| A | GLY242 |
| A | LYS296 |
| A | THR298 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE FMN B 2400 |
| Chain | Residue |
| B | SER103 |
| B | HIS104 |
| B | ARG123 |
| B | SER125 |
| B | LEU240 |
| B | ASN241 |
| B | LYS296 |
| B | THR298 |
| B | PRO299 |
| B | SER300 |
| B | ILE327 |
| B | ARG330 |
| B | HOH2411 |
| B | HOH2434 |
| B | HOH2458 |
| B | HOH2460 |
| B | HOH2481 |
| C | LEU280 |
| C | GLY281 |
| C | GLY282 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE FMN C 3400 |
| Chain | Residue |
| B | LEU280 |
| B | GLY281 |
| C | ARG50 |
| C | SER103 |
| C | HIS104 |
| C | ARG123 |
| C | SER125 |
| C | LEU240 |
| C | ASN241 |
| C | GLY242 |
| C | LYS296 |
| C | THR298 |
| C | PRO299 |
| C | SER300 |
| C | ILE327 |
| C | HOH3419 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN D 4400 |
| Chain | Residue |
| A | LEU280 |
| A | GLY281 |
| D | SER103 |
| D | HIS104 |
| D | ARG123 |
| D | SER125 |
| D | LEU240 |
| D | ASN241 |
| D | GLY242 |
| D | LYS296 |
| D | THR298 |
| D | PRO299 |
| D | SER300 |
| D | ILE327 |
| D | ARG330 |
| D | HOH4414 |
| D | HOH4433 |
| D | HOH4476 |
| D | HOH4514 |
Functional Information from PROSITE/UniProt
| site_id | PS00787 |
| Number of Residues | 16 |
| Details | CHORISMATE_SYNTHASE_1 Chorismate synthase signature 1. GESHGdvIGgVLDGmP |
| Chain | Residue | Details |
| A | GLY14-PRO29 |
| site_id | PS00788 |
| Number of Residues | 17 |
| Details | CHORISMATE_SYNTHASE_2 Chorismate synthase signature 2. GrsSAReSairVaaGAF |
| Chain | Residue | Details |
| A | GLY122-PHE138 |
| site_id | PS00789 |
| Number of Residues | 17 |
| Details | CHORISMATE_SYNTHASE_3 Chorismate synthase signature 3. RHDPCiairGsVVcESL |
| Chain | Residue | Details |
| A | ARG322-LEU338 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00300 |
| Chain | Residue | Details |
| A | ARG46 | |
| C | ASN241 | |
| C | GLY281 | |
| C | ARG322 | |
| D | ARG46 | |
| D | ASN241 | |
| D | GLY281 | |
| D | ARG322 | |
| A | ASN241 | |
| A | GLY281 | |
| A | ARG322 | |
| B | ARG46 | |
| B | ASN241 | |
| B | GLY281 | |
| B | ARG322 | |
| C | ARG46 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00300, ECO:0000269|PubMed:15095868 |
| Chain | Residue | Details |
| A | ARG123 | |
| A | LYS296 | |
| B | ARG123 | |
| B | LYS296 | |
| C | ARG123 | |
| C | LYS296 | |
| D | ARG123 | |
| D | LYS296 |
