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1UKW

Crystal structure of medium-chain acyl-CoA dehydrogenase from Thermus thermophilus HB8

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003995molecular_functionacyl-CoA dehydrogenase activity
A0016491molecular_functionoxidoreductase activity
A0016627molecular_functionoxidoreductase activity, acting on the CH-CH group of donors
A0050660molecular_functionflavin adenine dinucleotide binding
B0000166molecular_functionnucleotide binding
B0003995molecular_functionacyl-CoA dehydrogenase activity
B0016491molecular_functionoxidoreductase activity
B0016627molecular_functionoxidoreductase activity, acting on the CH-CH group of donors
B0050660molecular_functionflavin adenine dinucleotide binding
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CO B 411
ChainResidue
BASP176
BHIS177
BHOH1186

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE FAD A 420
ChainResidue
ASER188
ALEU388
AILE391
ATYR392
AGLU393
ATHR395
AGLU397
ALEU401
AHOH1010
AHOH1067
AHOH1201
BGLN309
APHE153
ALEU155
ASER156
AGLY161
ASER162
ATRP186

site_idAC3
Number of Residues21
DetailsBINDING SITE FOR RESIDUE FAD B 421
ChainResidue
AGLN309
BPHE153
BLEU155
BSER156
BGLY161
BSER162
BTRP186
BSER188
BLYS231
BLEU388
BILE391
BTYR392
BGLU393
BGLY394
BTHR395
BGLU397
BLEU401
BHOH1011
BHOH1025
BHOH1100
BHOH1149

Functional Information from PROSITE/UniProt
site_idPS00072
Number of Residues13
DetailsACYL_COA_DH_1 Acyl-CoA dehydrogenases signature 1. ALSEpgNGSDaaA
ChainResidueDetails
AALA154-ALA166

site_idPS00073
Number of Residues20
DetailsACYL_COA_DH_2 Acyl-CoA dehydrogenases signature 2. QiHGGyGYvrEfpveKllrD
ChainResidueDetails
AGLN366-ASP385

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ivh
ChainResidueDetails
ATHR272

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ivh
ChainResidueDetails
BTHR272

site_idCSA3
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ivh
ChainResidueDetails
AGLU393

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ivh
ChainResidueDetails
BGLU393

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PDB entries from 2024-11-06

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