1UKW
Crystal structure of medium-chain acyl-CoA dehydrogenase from Thermus thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0052890 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0052890 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO B 411 |
| Chain | Residue |
| B | ASP176 |
| B | HIS177 |
| B | HOH1186 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FAD A 420 |
| Chain | Residue |
| A | SER188 |
| A | LEU388 |
| A | ILE391 |
| A | TYR392 |
| A | GLU393 |
| A | THR395 |
| A | GLU397 |
| A | LEU401 |
| A | HOH1010 |
| A | HOH1067 |
| A | HOH1201 |
| B | GLN309 |
| A | PHE153 |
| A | LEU155 |
| A | SER156 |
| A | GLY161 |
| A | SER162 |
| A | TRP186 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD B 421 |
| Chain | Residue |
| A | GLN309 |
| B | PHE153 |
| B | LEU155 |
| B | SER156 |
| B | GLY161 |
| B | SER162 |
| B | TRP186 |
| B | SER188 |
| B | LYS231 |
| B | LEU388 |
| B | ILE391 |
| B | TYR392 |
| B | GLU393 |
| B | GLY394 |
| B | THR395 |
| B | GLU397 |
| B | LEU401 |
| B | HOH1011 |
| B | HOH1025 |
| B | HOH1100 |
| B | HOH1149 |
Functional Information from PROSITE/UniProt
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| A | THR272 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | THR272 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| A | GLU393 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | GLU393 |
