1UIM
Crystal Structure of Threonine Synthase from Thermus Thermophilus HB8, Orthorhombic Crystal Form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004795 | molecular_function | threonine synthase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006520 | biological_process | amino acid metabolic process |
A | 0009088 | biological_process | threonine biosynthetic process |
A | 0016829 | molecular_function | lyase activity |
A | 0019344 | biological_process | cysteine biosynthetic process |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 1901605 | biological_process | alpha-amino acid metabolic process |
B | 0004795 | molecular_function | threonine synthase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006520 | biological_process | amino acid metabolic process |
B | 0009088 | biological_process | threonine biosynthetic process |
B | 0016829 | molecular_function | lyase activity |
B | 0019344 | biological_process | cysteine biosynthetic process |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE PLP A 400 |
Chain | Residue |
A | PHE60 |
A | GLU287 |
A | THR317 |
A | GLY318 |
A | HOH405 |
A | HOH408 |
A | HOH433 |
A | LYS61 |
A | ASN87 |
A | GLY187 |
A | ASN188 |
A | ALA189 |
A | GLY190 |
A | ASN191 |
A | ALA240 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE PLP B 1400 |
Chain | Residue |
B | PHE60 |
B | LYS61 |
B | ASN87 |
B | VAL186 |
B | GLY187 |
B | ASN188 |
B | ALA189 |
B | GLY190 |
B | ASN191 |
B | ALA240 |
B | GLU287 |
B | THR317 |
B | GLY318 |
B | HOH1410 |
B | HOH1412 |
B | HOH1452 |
B | HOH1528 |
Functional Information from PROSITE/UniProt
site_id | PS00165 |
Number of Residues | 14 |
Details | DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site. Eglnp.TGSFKDRGM |
Chain | Residue | Details |
A | GLU52-MET65 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1pwh |
Chain | Residue | Details |
A | LYS61 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1pwh |
Chain | Residue | Details |
B | LYS61 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1pwh |
Chain | Residue | Details |
A | LYS61 | |
A | THR317 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1pwh |
Chain | Residue | Details |
B | LYS61 | |
B | THR317 |