1UEV
Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 0042245 | biological_process | RNA repair |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106354 | biological_process | tRNA surveillance |
| A | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | GLU59 |
| A | ASP61 |
| A | ASP110 |
| A | HOH687 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 602 |
| Chain | Residue |
| A | LYS166 |
| A | CA604 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 603 |
| Chain | Residue |
| A | THR383 |
| A | GLU387 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 604 |
| Chain | Residue |
| A | HOH614 |
| A | HOH675 |
| A | CA602 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP A 501 |
| Chain | Residue |
| A | VAL45 |
| A | GLY46 |
| A | SER47 |
| A | ARG50 |
| A | THR52 |
| A | TRP53 |
| A | LEU54 |
| A | GLU59 |
| A | ASP61 |
| A | THR130 |
| A | HIS133 |
| A | LYS152 |
| A | TYR161 |
| A | GLY172 |
| A | TYR173 |
| A | GLU176 |
| A | HOH686 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4O, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S |
| Chain | Residue | Details |
| A | SER47 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S |
| Chain | Residue | Details |
| A | ARG50 | |
| A | HIS133 | |
| A | LYS152 | |
| A | TYR161 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1UEV |
| Chain | Residue | Details |
| A | GLU59 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEV |
| Chain | Residue | Details |
| A | ASP61 | |
| A | ASP110 |
