1UC9

Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009085	biological_process	lysine biosynthetic process
A	0009432	biological_process	SOS response
A	0016874	molecular_function	ligase activity
A	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
A	0018169	molecular_function	ribosomal S6-glutamic acid ligase activity
A	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
A	0036211	biological_process	protein modification process
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0009085	biological_process	lysine biosynthetic process
B	0009432	biological_process	SOS response
B	0016874	molecular_function	ligase activity
B	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
B	0018169	molecular_function	ribosomal S6-glutamic acid ligase activity
B	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
B	0036211	biological_process	protein modification process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADP A 300

Chain	Residue
A	LYS129
A	PHE239
A	ASN248
A	GLN169
A	GLU170
A	TYR171
A	VAL172
A	LYS174
A	ASP178
A	ARG194
A	ASP237

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADP B 1300

Chain	Residue
B	LYS129
B	GLN169
B	GLU170
B	VAL172
B	LYS174
B	ASP178
B	ARG194
B	ASP237
B	PHE239
B	ASN248
B	GLU249

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	26
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1gsa

Chain	Residue	Details
A	ARG180
A	LYS129

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1gsa

Chain	Residue	Details
B	ARG180
B	LYS129

---