Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| A | 0004337 | molecular_function | geranyltranstransferase activity |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006695 | biological_process | cholesterol biosynthetic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0033384 | biological_process | geranyl diphosphate biosynthetic process |
| A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP117 |
| A | ASP121 |
| A | GPP401 |
| A | HOH463 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | ASP117 |
| A | ASP121 |
| A | ASP188 |
| A | GPP401 |
| A | HOH490 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GPP A 401 |
| Chain | Residue |
| A | SER113 |
| A | ASP117 |
| A | ASP121 |
| A | ARG126 |
| A | ASN144 |
| A | GLU182 |
| A | GLN185 |
| A | ASP188 |
| A | LYS214 |
| A | LYS280 |
| A | MG402 |
| A | MG403 |
| A | HOH456 |
Functional Information from PROSITE/UniProt
| site_id | PS00444 |
| Number of Residues | 13 |
| Details | POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGeyFQIqDDYlD |
| Chain | Residue | Details |
| A | MET249-ASP261 | |
| site_id | PS00723 |
| Number of Residues | 15 |
| Details | POLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVaDDim..DqsltRRG |
| Chain | Residue | Details |
| A | LEU114-GLY128 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS71 | |
| A | ARG74 | |
| A | GLN110 | |
| A | ARG127 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP117 | |
| A | ASP121 | |
| A | ARG126 | |
| A | LYS214 | |
| A | LYS280 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | THR215 | |
| A | GLN254 | |
| A | ALA271 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Important for determining product chain length |
| Chain | Residue | Details |
| A | ALA112 | |
| A | SER113 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1fps |
| Chain | Residue | Details |
| A | ARG126 | |
| A | PHE253 | |
| site_id | MCSA1 |
| Number of Residues | 10 |
| Details | M-CSA 253 |
| Chain | Residue | Details |
| A | LYS71 | electrostatic stabiliser |
| A | ASP258 | activator |
| A | ALA112 | steric role |
| A | ASP117 | metal ligand |
| A | ASP121 | metal ligand |
| A | ARG126 | electrostatic stabiliser |
| A | ASP188 | electrostatic stabiliser |
| A | LYS214 | electrostatic stabiliser |
| A | PHE253 | steric role |
| A | ASP257 | metal ligand |
