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1UAX

Crystal structure of the ribonuclease H2 from Pyrococcus horikoshii OT3

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003723molecular_functionRNA binding
A0004518molecular_functionnuclease activity
A0004519molecular_functionendonuclease activity
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
A0005737cellular_componentcytoplasm
A0006298biological_processmismatch repair
A0006401biological_processRNA catabolic process
A0016070biological_processRNA metabolic process
A0016787molecular_functionhydrolase activity
A0030145molecular_functionmanganese ion binding
A0032299cellular_componentribonuclease H2 complex
A0043137biological_processDNA replication, removal of RNA primer
A0046872molecular_functionmetal ion binding
B0003676molecular_functionnucleic acid binding
B0003723molecular_functionRNA binding
B0004518molecular_functionnuclease activity
B0004519molecular_functionendonuclease activity
B0004523molecular_functionRNA-DNA hybrid ribonuclease activity
B0005737cellular_componentcytoplasm
B0006298biological_processmismatch repair
B0006401biological_processRNA catabolic process
B0016070biological_processRNA metabolic process
B0016787molecular_functionhydrolase activity
B0030145molecular_functionmanganese ion binding
B0032299cellular_componentribonuclease H2 complex
B0043137biological_processDNA replication, removal of RNA primer
B0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues418
DetailsDomain: {"description":"RNase H type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01319","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues6
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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