1U7P
X-ray Crystal Structure of the Hypothetical Phosphotyrosine Phosphatase MDP-1 of the Haloacid Dehalogenase Superfamily
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0016791 | molecular_function | phosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0016791 | molecular_function | phosphatase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| D | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| D | 0016791 | molecular_function | phosphatase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | ASP11 |
| A | ASP13 |
| A | ASP123 |
| A | WO4505 |
| A | HOH533 |
| A | HOH564 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 502 |
| Chain | Residue |
| B | ASP122 |
| B | ASP123 |
| B | HOH597 |
| B | ASP11 |
| B | ASP13 |
| B | THR15 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 503 |
| Chain | Residue |
| C | ASP11 |
| C | ASP13 |
| C | ASP123 |
| C | WO4506 |
| C | HOH550 |
| C | HOH584 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 504 |
| Chain | Residue |
| D | ASP11 |
| D | ASP13 |
| D | ASP122 |
| D | ASP123 |
| D | HOH562 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE WO4 A 505 |
| Chain | Residue |
| A | ASP11 |
| A | LEU12 |
| A | ASP13 |
| A | SER69 |
| A | ARG70 |
| A | THR71 |
| A | LYS100 |
| A | MG501 |
| A | HOH571 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE WO4 C 506 |
| Chain | Residue |
| C | ASP11 |
| C | LEU12 |
| C | ASP13 |
| C | SER69 |
| C | ARG70 |
| C | THR71 |
| C | LYS100 |
| C | MG503 |
| C | HOH560 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP11 | |
| B | ASP11 | |
| C | ASP11 | |
| D | ASP11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP13 | |
| B | ASP13 | |
| C | ASP13 | |
| D | ASP13 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP11 | |
| B | SER69 | |
| B | LYS100 | |
| B | ASP123 | |
| C | ASP11 | |
| C | LEU12 | |
| C | ASP13 | |
| C | SER69 | |
| C | LYS100 | |
| C | ASP123 | |
| D | ASP11 | |
| A | LEU12 | |
| D | LEU12 | |
| D | ASP13 | |
| D | SER69 | |
| D | LYS100 | |
| D | ASP123 | |
| A | ASP13 | |
| A | SER69 | |
| A | LYS100 | |
| A | ASP123 | |
| B | ASP11 | |
| B | LEU12 | |
| B | ASP13 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | TRP20 | |
| A | ARG70 | |
| B | TRP20 | |
| B | ARG70 | |
| C | TRP20 | |
| C | ARG70 | |
| D | TRP20 | |
| D | ARG70 |
