1U7H
Structure and a Proposed Mechanism for Ornithine Cyclodeaminase from Pseudomonas putida
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008473 | molecular_function | ornithine cyclodeaminase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0055129 | biological_process | L-proline biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008473 | molecular_function | ornithine cyclodeaminase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0055129 | biological_process | L-proline biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 911 |
| Chain | Residue |
| A | ALA224 |
| A | VAL225 |
| A | GLY227 |
| A | SER293 |
| A | HOH992 |
| A | HOH994 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 912 |
| Chain | Residue |
| B | SER293 |
| B | HOH1104 |
| B | HOH1105 |
| B | ALA224 |
| B | VAL225 |
| B | GLY227 |
| site_id | AC3 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD B 801 |
| Chain | Residue |
| A | LYS331 |
| A | HOH1021 |
| A | HOH1143 |
| B | THR84 |
| B | ARG112 |
| B | THR113 |
| B | GLY138 |
| B | ALA139 |
| B | GLN140 |
| B | ASP161 |
| B | THR162 |
| B | VAL201 |
| B | THR202 |
| B | ALA203 |
| B | ILE210 |
| B | VAL225 |
| B | GLY226 |
| B | ASP228 |
| B | LYS232 |
| B | SER293 |
| B | VAL294 |
| B | GLY295 |
| B | HOH1080 |
| B | HOH1087 |
| B | HOH1096 |
| B | HOH1097 |
| B | HOH1101 |
| B | HOH1109 |
| B | HOH1143 |
| B | HOH1144 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD A 802 |
| Chain | Residue |
| A | THR84 |
| A | ARG112 |
| A | THR113 |
| A | GLY138 |
| A | ALA139 |
| A | GLN140 |
| A | ASP161 |
| A | THR162 |
| A | VAL201 |
| A | THR202 |
| A | ALA203 |
| A | ILE210 |
| A | VAL225 |
| A | GLY226 |
| A | ASP228 |
| A | LYS232 |
| A | SER293 |
| A | VAL294 |
| A | GLY295 |
| A | HOH971 |
| A | HOH973 |
| A | HOH977 |
| A | HOH998 |
| A | HOH1002 |
| A | HOH1003 |
| A | HOH1004 |
| A | HOH1016 |
| A | HOH1018 |
| A | HOH1211 |
| B | LYS331 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 901 |
| Chain | Residue |
| A | GLN38 |
| A | ALA39 |
| A | ALA61 |
| A | ASP62 |
| A | LYS63 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD A 902 |
| Chain | Residue |
| A | ALA39 |
| A | HOH1149 |
| A | HOH1150 |
| B | LEU216 |
| B | PRO218 |
| B | SER286 |
| B | VAL288 |
| B | HOH992 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MPD B 903 |
| Chain | Residue |
| B | SER64 |
| B | ARG65 |
| B | ALA92 |
| B | ASP93 |
| B | VAL100 |
| B | LEU308 |
| B | HOH1254 |
| B | HOH1255 |
| B | HOH1256 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 904 |
| Chain | Residue |
| A | TYR3 |
| A | ALA311 |
| A | GLU312 |
| A | GLY315 |
| A | MSE316 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD B 905 |
| Chain | Residue |
| B | TYR3 |
| B | ALA311 |
| B | GLU312 |
| B | GLY315 |
| B | MSE316 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"15518536","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1X7D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15518536","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1X7D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15518536","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1U7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X7D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 717 |
| Chain | Residue | Details |
| A | VAL60 | increase nucleophilicity, proton acceptor, proton donor |
| A | GLU256 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 717 |
| Chain | Residue | Details |
| B | VAL60 | increase nucleophilicity, proton acceptor, proton donor |
| B | GLU256 | proton acceptor, proton donor |
