1U6Z
Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004309 | molecular_function | exopolyphosphatase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006793 | biological_process | phosphorus metabolic process |
| A | 0006798 | biological_process | polyphosphate catabolic process |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0004309 | molecular_function | exopolyphosphatase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006793 | biological_process | phosphorus metabolic process |
| B | 0006798 | biological_process | polyphosphate catabolic process |
| B | 0016462 | molecular_function | pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 A 701 |
| Chain | Residue |
| A | GLY19 |
| A | HOH1025 |
| A | HOH1089 |
| A | HOH1090 |
| A | SER20 |
| A | THR89 |
| A | GLY145 |
| A | GLY146 |
| A | GLY147 |
| A | SER148 |
| A | HOH952 |
| A | HOH957 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 702 |
| Chain | Residue |
| A | ASN21 |
| A | SER217 |
| A | GLY218 |
| A | ARG267 |
| A | HOH1059 |
| A | HOH1099 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 703 |
| Chain | Residue |
| A | LYS42 |
| A | ARG44 |
| A | SER264 |
| A | ARG267 |
| A | HOH1035 |
| A | HOH1102 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 704 |
| Chain | Residue |
| A | TRP210 |
| A | ILE287 |
| A | ARG288 |
| A | GLU289 |
| A | HOH1098 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 705 |
| Chain | Residue |
| A | HIS378 |
| A | ARG413 |
| A | HOH1020 |
| A | HOH1145 |
| A | HOH1204 |
| B | THR200 |
| B | HOH1011 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 706 |
| Chain | Residue |
| A | ARG165 |
| A | ARG166 |
| A | LYS197 |
| A | HOH1106 |
| A | HOH1107 |
| A | HOH1160 |
| A | HOH1190 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 707 |
| Chain | Residue |
| A | SER379 |
| A | GLY380 |
| A | ARG413 |
| B | ARG166 |
| B | HOH1010 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 708 |
| Chain | Residue |
| A | LYS428 |
| A | LYS429 |
| A | HOH1012 |
| A | HOH1016 |
| A | HOH1064 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 709 |
| Chain | Residue |
| A | LYS428 |
| A | LYS430 |
| A | GLN431 |
| A | HOH1141 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 710 |
| Chain | Residue |
| A | HIS356 |
| A | PRO357 |
| A | GLN358 |
| A | HOH1154 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 711 |
| Chain | Residue |
| A | SER316 |
| A | ARG364 |
| A | TRP365 |
| A | MET368 |
| A | HOH1126 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 712 |
| Chain | Residue |
| A | HIS466 |
| A | GLY498 |
| A | ARG500 |
| A | HOH1209 |
| site_id | BC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 B 801 |
| Chain | Residue |
| B | GLY19 |
| B | SER20 |
| B | THR89 |
| B | HIS90 |
| B | GLU121 |
| B | GLY145 |
| B | GLY146 |
| B | GLY147 |
| B | SER148 |
| B | HOH846 |
| B | HOH982 |
| B | HOH1018 |
| B | HOH1129 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 802 |
| Chain | Residue |
| B | ASN21 |
| B | SER22 |
| B | SER217 |
| B | GLY218 |
| B | ARG267 |
| B | HOH877 |
| B | HOH972 |
| B | HOH993 |
| B | HOH1108 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 803 |
| Chain | Residue |
| B | LYS42 |
| B | SER264 |
| B | ARG267 |
| B | SO4814 |
| B | HOH854 |
| B | HOH923 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 804 |
| Chain | Residue |
| B | ARG288 |
| B | GLU289 |
| B | HOH1063 |
| B | HOH1071 |
| B | TRP210 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 805 |
| Chain | Residue |
| A | THR200 |
| B | ARG413 |
| B | ASN447 |
| B | HOH852 |
| B | HOH998 |
| B | HOH999 |
| B | HOH1000 |
| B | HOH1137 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 806 |
| Chain | Residue |
| B | ARG165 |
| B | ARG166 |
| B | LYS197 |
| B | HOH1010 |
| B | HOH1050 |
| B | HOH1052 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 807 |
| Chain | Residue |
| B | SER379 |
| B | GLY380 |
| B | HIS382 |
| B | ARG413 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 808 |
| Chain | Residue |
| B | LYS428 |
| B | LYS429 |
| B | HOH1092 |
| B | HOH1099 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 809 |
| Chain | Residue |
| B | LYS353 |
| B | LYS428 |
| B | LYS430 |
| B | GLN431 |
| B | HOH1094 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 810 |
| Chain | Residue |
| B | HIS356 |
| B | PRO357 |
| B | GLN358 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 811 |
| Chain | Residue |
| B | SER316 |
| B | ARG364 |
| B | TRP365 |
| B | HOH902 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 812 |
| Chain | Residue |
| B | HIS466 |
| B | ALA497 |
| B | GLY498 |
| B | ARG500 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 813 |
| Chain | Residue |
| B | ASP49 |
| B | GLY50 |
| B | SER58 |
| B | GLU60 |
| B | ARG64 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 814 |
| Chain | Residue |
| A | SER330 |
| A | HOH995 |
| A | HOH1004 |
| A | HOH1046 |
| B | LYS42 |
| B | LYS221 |
| B | SO4803 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 815 |
| Chain | Residue |
| A | HIS327 |
| B | SER264 |
| B | GLU265 |
| B | HOH947 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 816 |
| Chain | Residue |
| B | HIS46 |
| B | ARG64 |
| B | ARG138 |
| B | GLN208 |
| B | HOH1116 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 901 |
| Chain | Residue |
| A | HIS327 |
| A | HOH977 |
| A | HOH1164 |
| B | PRO261 |
| B | HIS327 |
