Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001523 | biological_process | retinoid metabolic process |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0004745 | molecular_function | all-trans-retinol dehydrogenase (NAD+) activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005929 | cellular_component | cilium |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0036064 | cellular_component | ciliary basal body |
| A | 0042572 | biological_process | retinol metabolic process |
| A | 0042573 | biological_process | retinoic acid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0001523 | biological_process | retinoid metabolic process |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0004745 | molecular_function | all-trans-retinol dehydrogenase (NAD+) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005929 | cellular_component | cilium |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0036064 | cellular_component | ciliary basal body |
| B | 0042572 | biological_process | retinol metabolic process |
| B | 0042573 | biological_process | retinoic acid metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 375 |
| Chain | Residue |
| A | CYS97 |
| A | CYS100 |
| A | CYS103 |
| A | CYS111 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 376 |
| Chain | Residue |
| A | CYS46 |
| A | HIS67 |
| A | CYS174 |
| A | NAD1377 |
| A | HPL1378 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 375 |
| Chain | Residue |
| B | CYS97 |
| B | CYS100 |
| B | CYS103 |
| B | CYS111 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 376 |
| Chain | Residue |
| B | CYS46 |
| B | HIS67 |
| B | CYS174 |
| B | NAD2377 |
| B | HPL2378 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1400 |
| Chain | Residue |
| A | SER1 |
| A | LYS5 |
| A | HOH1469 |
| A | HOH1527 |
| B | THR127 |
| B | ARG128 |
| B | HOH2407 |
| B | HOH2440 |
| B | HOH2798 |
| site_id | AC6 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD A 1377 |
| Chain | Residue |
| A | ARG47 |
| A | THR48 |
| A | HIS51 |
| A | PHE93 |
| A | CYS174 |
| A | THR178 |
| A | GLY199 |
| A | LEU200 |
| A | GLY201 |
| A | GLY202 |
| A | VAL203 |
| A | ASP223 |
| A | ILE224 |
| A | LYS228 |
| A | VAL268 |
| A | ILE269 |
| A | ARG271 |
| A | VAL292 |
| A | GLY293 |
| A | VAL294 |
| A | ALA317 |
| A | VAL318 |
| A | TYR319 |
| A | LEU362 |
| A | ARG369 |
| A | ZN376 |
| A | HPL1378 |
| A | HOH1387 |
| A | HOH1416 |
| A | HOH1466 |
| A | HOH1502 |
| A | HOH1508 |
| A | HOH1619 |
| A | HOH1668 |
| A | HOH1744 |
| A | HOH1781 |
| site_id | AC7 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD B 2377 |
| Chain | Residue |
| B | ARG47 |
| B | THR48 |
| B | HIS51 |
| B | PHE93 |
| B | CYS174 |
| B | THR178 |
| B | GLY199 |
| B | LEU200 |
| B | GLY201 |
| B | GLY202 |
| B | VAL203 |
| B | ASP223 |
| B | ILE224 |
| B | LYS228 |
| B | VAL268 |
| B | ILE269 |
| B | ARG271 |
| B | THR274 |
| B | VAL292 |
| B | GLY293 |
| B | VAL294 |
| B | ALA317 |
| B | VAL318 |
| B | TYR319 |
| B | ARG369 |
| B | ZN376 |
| B | HPL2378 |
| B | HOH2384 |
| B | HOH2389 |
| B | HOH2456 |
| B | HOH2487 |
| B | HOH2491 |
| B | HOH2592 |
| B | HOH2641 |
| B | HOH2662 |
| B | HOH2838 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HPL A 1378 |
| Chain | Residue |
| A | CYS46 |
| A | THR48 |
| A | LEU57 |
| A | HIS67 |
| A | PHE93 |
| A | LEU116 |
| A | LEU141 |
| A | CYS174 |
| A | VAL294 |
| A | ZN376 |
| A | NAD1377 |
| A | HOH1878 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HPL B 2378 |
| Chain | Residue |
| A | MET306 |
| B | CYS46 |
| B | THR48 |
| B | HIS67 |
| B | PHE93 |
| B | CYS174 |
| B | VAL294 |
| B | ZN376 |
| B | NAD2377 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesvGegV |
| Chain | Residue | Details |
| A | GLY66-VAL80 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ARG47 | |
| A | PHE229 | |
| A | GLY293 | |
| A | THR370 | |
| B | ARG47 | |
| B | GLU68 | |
| B | GLY98 | |
| B | ARG101 | |
| B | LYS104 | |
| B | LEU112 | |
| B | GLY175 | |
| A | GLU68 | |
| B | LEU200 | |
| B | ILE224 | |
| B | PHE229 | |
| B | GLY293 | |
| B | THR370 | |
| A | GLY98 | |
| A | ARG101 | |
| A | LYS104 | |
| A | LEU112 | |
| A | GLY175 | |
| A | LEU200 | |
| A | ILE224 | |
| Chain | Residue | Details |
| A | THR2 | |
| B | THR2 | |
| Chain | Residue | Details |
| A | ILE23 | |
| B | ILE23 | |
| Chain | Residue | Details |
| A | GLU35 | |
| B | GLU35 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | THR48 | |
| A | ARG47 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | THR48 | |
| B | ARG47 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | LEU57 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | LEU57 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | THR48 | |
| A | HIS51 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | THR48 | |
| B | HIS51 | |
