Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0030272 | molecular_function | 5-formyltetrahydrofolate cyclo-ligase activity |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A 201 |
| Chain | Residue |
| A | ARG115 |
| A | THF501 |
| A | HOH613 |
| A | GLY117 |
| A | PHE118 |
| A | GLY119 |
| A | LYS120 |
| A | GLY121 |
| A | TYR122 |
| A | TYR123 |
| A | ADP301 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | LYS3 |
| A | ASP124 |
| A | ASP154 |
| A | ADP301 |
| A | HOH662 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP A 301 |
| Chain | Residue |
| A | LYS3 |
| A | ARG7 |
| A | GLY117 |
| A | PHE118 |
| A | GLY119 |
| A | LYS120 |
| A | GLY121 |
| A | ASP124 |
| A | ARG125 |
| A | MET128 |
| A | TRP153 |
| A | ASP154 |
| A | PO4201 |
| A | MG401 |
| A | HOH613 |
| A | HOH662 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE THF A 501 |
| Chain | Residue |
| A | TYR49 |
| A | GLU50 |
| A | ILE52 |
| A | GLU55 |
| A | PRO76 |
| A | PRO105 |
| A | ARG115 |
| A | PHE118 |
| A | TYR123 |
| A | PO4201 |
| A | HOH608 |
| A | HOH670 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS3 | |
| A | ARG125 | |
| A | TRP153 | |
| Chain | Residue | Details |
| A | GLU50 | |
| A | GLU55 | |
| A | ASP124 | |
| A | ASP154 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ARG115 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 541 |
| Chain | Residue | Details |
| A | ARG115 | electrostatic stabiliser, increase electrophilicity |
| A | ASP124 | metal ligand |
| A | ASP154 | metal ligand |
