1U1H

A. thaliana cobalamine independent methionine synthase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000325	cellular_component	plant-type vacuole
A	0003729	molecular_function	mRNA binding
A	0003871	molecular_function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005777	cellular_component	peroxisome
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006346	biological_process	DNA methylation-dependent heterochromatin formation
A	0008168	molecular_function	methyltransferase activity
A	0008172	molecular_function	S-methyltransferase activity
A	0008270	molecular_function	zinc ion binding
A	0008652	biological_process	amino acid biosynthetic process
A	0008705	molecular_function	methionine synthase activity
A	0009086	biological_process	methionine biosynthetic process
A	0009506	cellular_component	plasmodesma
A	0009507	cellular_component	chloroplast
A	0009570	cellular_component	chloroplast stroma
A	0010043	biological_process	response to zinc ion
A	0032259	biological_process	methylation
A	0046872	molecular_function	metal ion binding
A	0048046	cellular_component	apoplast
A	0051574	biological_process	obsolete positive regulation of histone H3-K9 methylation
A	0071266	biological_process	'de novo' L-methionine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 766

Chain	Residue
A	HIS647
A	CYS649
A	CYS733
A	MET772
A	HOH773

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 767

Chain	Residue
A	HIS135
A	GLU194
A	HIS658
A	ASP662

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 768

Chain	Residue
A	PRO79
A	PRO80
A	ARG81
A	HOH798

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 769

Chain	Residue
A	ARG610
A	TYR650
A	SER651
A	HIS652

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 770

Chain	Residue
A	LYS55
A	PHE56
A	ASP150
A	THR201

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 771

Chain	Residue
A	PRO575
A	ARG576
A	HIS577
A	TRP626

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MET A 772

Chain	Residue
A	ILE437
A	GLY438
A	SER439
A	GLU490
A	MSE496
A	MSE557
A	ASP605
A	HIS647
A	CYS649
A	GLY734
A	ZN766

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P82610

Chain	Residue	Details
A	HIS701

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15326182, ECO:0007744|PDB:1U1J, ECO:0007744|PDB:1U22

Chain	Residue	Details
A	LYS18
A	ARG521
A	TRP567

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15326182, ECO:0007744|PDB:1U1J

Chain	Residue	Details
A	ASN116

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15326182, ECO:0007744|PDB:1U1H, ECO:0007744|PDB:1U1J

Chain	Residue	Details
A	ILE437
A	GLU490
A	ASP605

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15326182, ECO:0007744|PDB:1U1H, ECO:0007744|PDB:1U1J, ECO:0007744|PDB:1U1U, ECO:0007744|PDB:1U22

Chain	Residue	Details
A	HIS647
A	HIS658
A	ASP662

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15326182, ECO:0007744|PDB:1U1H, ECO:0007744|PDB:1U1J, ECO:0007744|PDB:1U22

Chain	Residue	Details
A	CYS649
A	CYS733

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P82610

Chain	Residue	Details
A	GLU671

---