1TXN
Crystal structure of coproporphyrinogen III oxidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004109 | molecular_function | coproporphyrinogen oxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0004109 | molecular_function | coproporphyrinogen oxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 500 |
| Chain | Residue |
| A | ARG188 |
| A | PHE213 |
| A | ASP214 |
| A | TYR216 |
| A | HOH529 |
| A | HOH540 |
| A | HOH566 |
| A | HOH695 |
Functional Information from PROSITE/UniProt
| site_id | PS01021 |
| Number of Residues | 25 |
| Details | COPROGEN_OXIDASE Coproporphyrinogen III oxidase signature. KkWCdeYFyItHRkEtRGIGGIFFD |
| Chain | Residue | Details |
| A | LYS190-ASP214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS131 | |
| B | HIS131 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER117 | |
| A | ASN133 | |
| A | GLY285 | |
| B | SER117 | |
| B | ASN133 | |
| B | GLY285 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Important for dimerization => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS201 | |
| B | HIS201 |
