1TTE

The Structure of a Class II ubiquitin-conjugating enzyme, Ubc1.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000209	biological_process	protein polyubiquitination
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0016050	biological_process	vesicle organization
A	0016567	biological_process	protein ubiquitination
A	0016740	molecular_function	transferase activity
A	0019538	biological_process	protein metabolic process
A	0036503	biological_process	ERAD pathway
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0061631	molecular_function	ubiquitin conjugating enzyme activity
A	0070628	molecular_function	proteasome binding

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	17
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIssvtGaICLdiL

Chain	Residue	Details
A	TYR76-LEU92

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388

Chain	Residue	Details
A	CYS88

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047

Chain	Residue	Details
A	ARG93

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