1TT3

NMR soulution structure of omega-conotoxin [K10]MVIIA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008200	molecular_function	ion channel inhibitor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NH2 A 26

Chain	Residue
A	SER19
A	CYS25

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Functional Information from PROSITE/UniProt

site_id	PS60004
Number of Residues	25
Details	OMEGA_CONOTOXIN Omega-conotoxin family signature. CKgkGaKCSkl...MYdCCTg.SCr..SGKC

Chain	Residue	Details
A	CYS1-CYS25

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Peptide: {"description":"Omega-conotoxin MVIIA","featureId":"PRO_0000034915","evidences":[{"source":"PubMed","id":"2441741","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"4071055","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Site: {"description":"Binds Cav2.2/CACNA1B calcium channel","evidences":[{"source":"PubMed","id":"34234349","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Binds Cav2.2/CACNA1B calcium channel","evidences":[{"source":"PubMed","id":"30194442","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34234349","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7826361","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"2441741","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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