1TT1
CRYSTAL STRUCTURE OF THE GLUR6 LIGAND BINDING CORE IN COMPLEX WITH KAINATE 1.93 A RESOLUTION
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KAI A 998 |
| Chain | Residue |
| A | TYR61 |
| A | ASN174 |
| A | GLU191 |
| A | HOH1000 |
| A | HOH1005 |
| A | HOH1014 |
| A | PRO89 |
| A | LEU90 |
| A | ALA91 |
| A | ARG96 |
| A | VAL138 |
| A | GLY141 |
| A | ALA142 |
| A | THR143 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KAI B 999 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | ALA91 |
| B | ARG96 |
| B | VAL138 |
| B | GLY141 |
| B | ALA142 |
| B | THR143 |
| B | ASN174 |
| B | GLU191 |
| B | HOH1000 |
| B | HOH1012 |
| B | HOH1021 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR135-TYR155 | |
| A | ILE212-THR232 | |
| B | TYR135-TYR155 | |
| B | ILE212-THR232 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 110 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:8163463 |
| Chain | Residue | Details |
| A | ASP156-LEU211 | |
| B | ASP156-LEU211 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15721240, ECO:0000269|PubMed:17115050, ECO:0007744|PDB:1S50, ECO:0007744|PDB:1S7Y, ECO:0007744|PDB:2I0B, ECO:0007744|PDB:2I0C |
| Chain | Residue | Details |
| A | PRO89 | |
| B | ALA142 | |
| B | THR143 | |
| B | GLU191 | |
| A | ALA91 | |
| A | ARG96 | |
| A | ALA142 | |
| A | THR143 | |
| A | GLU191 | |
| B | PRO89 | |
| B | ALA91 | |
| B | ARG96 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| A | THR119 | |
| B | ASN3 | |
| B | THR119 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15677325, ECO:0000269|PubMed:8163463 |
| Chain | Residue | Details |
| A | ASN204 | |
| B | ASN204 |
